##Databases: KEGG PATHWAY, Gene Ontology ##Statistical test method: hypergeometric test / Fisher's exact test ##FDR correction method: Benjamini and Hochberg #Term Database ID Input number Background number P-Value Corrected P-Value Input Hyperlink Cytokine-cytokine receptor interaction KEGG PATHWAY hsa04060 5 294 0.000519379180745 0.0601614217697 56477|6354|6352|8600|130399 http://www.genome.jp/kegg-bin/show_pathway?hsa04060/hsa:6354%09red/hsa:130399%09red/hsa:56477%09red/hsa:8600%09red/hsa:6352%09red Primary bile acid biosynthesis KEGG PATHWAY hsa00120 2 17 0.000790455310718 0.065311276852 9420|1593 http://www.genome.jp/kegg-bin/show_pathway?hsa00120/hsa:1593%09red/hsa:9420%09red Rheumatoid arthritis KEGG PATHWAY hsa05323 3 91 0.00117539197486 0.0680747852108 8600|527|6352 http://www.genome.jp/kegg-bin/show_pathway?hsa05323/hsa:527%09red/hsa:8600%09red/hsa:6352%09red Viral protein interaction with cytokine and cytokine receptor KEGG PATHWAY hsa04061 3 100 0.00152896724585 0.0759023025617 56477|6354|6352 http://www.genome.jp/kegg-bin/show_pathway?hsa04061/hsa:6354%09red/hsa:56477%09red/hsa:6352%09red Chagas disease (American trypanosomiasis) KEGG PATHWAY hsa05142 3 103 0.00166004859803 0.0769155850421 5521|6352|1636 http://www.genome.jp/kegg-bin/show_pathway?hsa05142/hsa:1636%09red/hsa:5521%09red/hsa:6352%09red Prion diseases KEGG PATHWAY hsa05020 2 35 0.00300090581005 0.0935011358162 733|6352 http://www.genome.jp/kegg-bin/show_pathway?hsa05020/hsa:733%09red/hsa:6352%09red Natural killer cell mediated cytotoxicity KEGG PATHWAY hsa04650 3 131 0.00322881620085 0.0935011358162 80329|5777|2207 http://www.genome.jp/kegg-bin/show_pathway?hsa04650/hsa:5777%09red/hsa:2207%09red/hsa:80329%09red ABC transporters KEGG PATHWAY hsa02010 2 45 0.00480230167535 0.119199988013 1244|10058 http://www.genome.jp/kegg-bin/show_pathway?hsa02010/hsa:10058%09red/hsa:1244%09red Chemokine signaling pathway KEGG PATHWAY hsa04062 3 190 0.00885858650018 0.144787317268 56477|6354|6352 http://www.genome.jp/kegg-bin/show_pathway?hsa04062/hsa:6354%09red/hsa:56477%09red/hsa:6352%09red Epithelial cell signaling in Helicobacter pylori infection KEGG PATHWAY hsa05120 2 70 0.0109608096311 0.144787317268 527|6352 http://www.genome.jp/kegg-bin/show_pathway?hsa05120/hsa:527%09red/hsa:6352%09red Sphingolipid signaling pathway KEGG PATHWAY hsa04071 2 119 0.0290624767638 0.160059682359 5521|2207 http://www.genome.jp/kegg-bin/show_pathway?hsa04071/hsa:2207%09red/hsa:5521%09red Human papillomavirus infection KEGG PATHWAY hsa05165 3 330 0.03687981656 0.170876483395 5521|527|55502 http://www.genome.jp/kegg-bin/show_pathway?hsa05165/hsa:527%09red/hsa:55502%09red/hsa:5521%09red One carbon pool by folate KEGG PATHWAY hsa00670 1 20 0.0449896062261 0.178673007584 10841 http://www.genome.jp/kegg-bin/show_pathway?hsa00670/hsa:10841%09red Histidine metabolism KEGG PATHWAY hsa00340 1 23 0.0512512248748 0.18266462199 10841 http://www.genome.jp/kegg-bin/show_pathway?hsa00340/hsa:10841%09red Renin-angiotensin system KEGG PATHWAY hsa04614 1 23 0.0512512248748 0.18266462199 1636 http://www.genome.jp/kegg-bin/show_pathway?hsa04614/hsa:1636%09red RNA transport KEGG PATHWAY hsa03013 2 165 0.0520427586699 0.184397681977 8663|79897 http://www.genome.jp/kegg-bin/show_pathway?hsa03013/hsa:8663%09red/hsa:79897%09red Collecting duct acid secretion KEGG PATHWAY hsa04966 1 27 0.0595369779571 0.198933652308 527 http://www.genome.jp/kegg-bin/show_pathway?hsa04966/hsa:527%09red Tuberculosis KEGG PATHWAY hsa05152 2 179 0.0599874984188 0.199479958857 527|2207 http://www.genome.jp/kegg-bin/show_pathway?hsa05152/hsa:527%09red/hsa:2207%09red Circadian rhythm KEGG PATHWAY hsa04710 1 31 0.0677512126441 0.203840228518 6096 http://www.genome.jp/kegg-bin/show_pathway?hsa04710/hsa:6096%09red Antifolate resistance KEGG PATHWAY hsa01523 1 31 0.0677512126441 0.203840228518 1244 http://www.genome.jp/kegg-bin/show_pathway?hsa01523/hsa:1244%09red Mucin type O-glycan biosynthesis KEGG PATHWAY hsa00512 1 31 0.0677512126441 0.203840228518 57452 http://www.genome.jp/kegg-bin/show_pathway?hsa00512/hsa:57452%09red Asthma KEGG PATHWAY hsa05310 1 31 0.0677512126441 0.203840228518 2207 http://www.genome.jp/kegg-bin/show_pathway?hsa05310/hsa:2207%09red Type I diabetes mellitus KEGG PATHWAY hsa04940 1 43 0.0919708809119 0.232394370319 3382 http://www.genome.jp/kegg-bin/show_pathway?hsa04940/hsa:3382%09red Notch signaling pathway KEGG PATHWAY hsa04330 1 48 0.101877914539 0.24165580411 23220 http://www.genome.jp/kegg-bin/show_pathway?hsa04330/hsa:23220%09red Intestinal immune network for IgA production KEGG PATHWAY hsa04672 1 49 0.103846464752 0.24431385993 56477 http://www.genome.jp/kegg-bin/show_pathway?hsa04672/hsa:56477%09red Vibrio cholerae infection KEGG PATHWAY hsa05110 1 50 0.105810750847 0.24431385993 527 http://www.genome.jp/kegg-bin/show_pathway?hsa05110/hsa:527%09red Cholesterol metabolism KEGG PATHWAY hsa04979 1 50 0.105810750847 0.24431385993 1593 http://www.genome.jp/kegg-bin/show_pathway?hsa04979/hsa:1593%09red Steroid hormone biosynthesis KEGG PATHWAY hsa00140 1 60 0.125221083721 0.260653830548 9420 http://www.genome.jp/kegg-bin/show_pathway?hsa00140/hsa:9420%09red Cytosolic DNA-sensing pathway KEGG PATHWAY hsa04623 1 63 0.130962561885 0.262302537493 6352 http://www.genome.jp/kegg-bin/show_pathway?hsa04623/hsa:6352%09red Retinol metabolism KEGG PATHWAY hsa00830 1 67 0.138559974067 0.265287002691 8608 http://www.genome.jp/kegg-bin/show_pathway?hsa00830/hsa:8608%09red Fc epsilon RI signaling pathway KEGG PATHWAY hsa04664 1 68 0.140449048194 0.26669969534 2207 http://www.genome.jp/kegg-bin/show_pathway?hsa04664/hsa:2207%09red Renin secretion KEGG PATHWAY hsa04924 1 69 0.142334028351 0.268521277381 1636 http://www.genome.jp/kegg-bin/show_pathway?hsa04924/hsa:1636%09red Prolactin signaling pathway KEGG PATHWAY hsa04917 1 70 0.144214923307 0.270890193779 8600 http://www.genome.jp/kegg-bin/show_pathway?hsa04917/hsa:8600%09red Bile secretion KEGG PATHWAY hsa04976 1 72 0.147964492588 0.275388794291 1244 http://www.genome.jp/kegg-bin/show_pathway?hsa04976/hsa:1244%09red Adherens junction KEGG PATHWAY hsa04520 1 72 0.147964492588 0.275388794291 5777 http://www.genome.jp/kegg-bin/show_pathway?hsa04520/hsa:5777%09red Platinum drug resistance KEGG PATHWAY hsa01524 1 73 0.149833184356 0.27671913106 1244 http://www.genome.jp/kegg-bin/show_pathway?hsa01524/hsa:1244%09red Leishmaniasis KEGG PATHWAY hsa05140 1 74 0.151697825804 0.27671913106 5777 http://www.genome.jp/kegg-bin/show_pathway?hsa05140/hsa:5777%09red PPAR signaling pathway KEGG PATHWAY hsa03320 1 76 0.155414992424 0.279104443759 1593 http://www.genome.jp/kegg-bin/show_pathway?hsa03320/hsa:1593%09red Synaptic vesicle cycle KEGG PATHWAY hsa04721 1 78 0.159116061626 0.283552981615 527 http://www.genome.jp/kegg-bin/show_pathway?hsa04721/hsa:527%09red Complement and coagulation cascades KEGG PATHWAY hsa04610 1 79 0.160960581233 0.284650391747 733 http://www.genome.jp/kegg-bin/show_pathway?hsa04610/hsa:733%09red B cell receptor signaling pathway KEGG PATHWAY hsa04662 1 82 0.166470183021 0.285984445074 5777 http://www.genome.jp/kegg-bin/show_pathway?hsa04662/hsa:5777%09red PD-L1 expression and PD-1 checkpoint pathway in cancer KEGG PATHWAY hsa05235 1 89 0.179187264559 0.295807954558 5777 http://www.genome.jp/kegg-bin/show_pathway?hsa05235/hsa:5777%09red Hypertrophic cardiomyopathy (HCM) KEGG PATHWAY hsa05410 1 90 0.180988268264 0.295969050455 1636 http://www.genome.jp/kegg-bin/show_pathway?hsa05410/hsa:1636%09red mRNA surveillance pathway KEGG PATHWAY hsa03015 1 91 0.182785366648 0.297507798174 5521 http://www.genome.jp/kegg-bin/show_pathway?hsa03015/hsa:5521%09red IL-17 signaling pathway KEGG PATHWAY hsa04657 1 93 0.186367880907 0.299827956552 6354 http://www.genome.jp/kegg-bin/show_pathway?hsa04657/hsa:6354%09red GnRH signaling pathway KEGG PATHWAY hsa04912 1 93 0.186367880907 0.299827956552 2797 http://www.genome.jp/kegg-bin/show_pathway?hsa04912/hsa:2797%09red TGF-beta signaling pathway KEGG PATHWAY hsa04350 1 94 0.188153313465 0.301305421332 130399 http://www.genome.jp/kegg-bin/show_pathway?hsa04350/hsa:130399%09red Amoebiasis KEGG PATHWAY hsa05146 1 95 0.189934874067 0.303459166613 733 http://www.genome.jp/kegg-bin/show_pathway?hsa05146/hsa:733%09red NF-kappa B signaling pathway KEGG PATHWAY hsa04064 1 100 0.198784887525 0.315423508744 8600 http://www.genome.jp/kegg-bin/show_pathway?hsa04064/hsa:8600%09red T cell receptor signaling pathway KEGG PATHWAY hsa04660 1 103 0.204048960449 0.320846216091 5777 http://www.genome.jp/kegg-bin/show_pathway?hsa04660/hsa:5777%09red C-type lectin receptor signaling pathway KEGG PATHWAY hsa04625 1 104 0.205796044719 0.32141180018 2207 http://www.genome.jp/kegg-bin/show_pathway?hsa04625/hsa:2207%09red Toll-like receptor signaling pathway KEGG PATHWAY hsa04620 1 104 0.205796044719 0.32141180018 6352 http://www.genome.jp/kegg-bin/show_pathway?hsa04620/hsa:6352%09red Metabolic pathways KEGG PATHWAY hsa01100 5 1433 0.207124295719 0.322760954091 10841|8608|527|57452|1593 http://www.genome.jp/kegg-bin/show_pathway?hsa01100/hsa:1593%09red/hsa:527%09red/hsa:10841%09red/hsa:8608%09red/hsa:57452%09red Parathyroid hormone synthesis, secretion and action KEGG PATHWAY hsa04928 1 106 0.209278852071 0.325388819215 8600 http://www.genome.jp/kegg-bin/show_pathway?hsa04928/hsa:8600%09red TNF signaling pathway KEGG PATHWAY hsa04668 1 112 0.219636967315 0.334021208499 6352 http://www.genome.jp/kegg-bin/show_pathway?hsa04668/hsa:6352%09red AMPK signaling pathway KEGG PATHWAY hsa04152 1 120 0.233239467225 0.344164394313 5521 http://www.genome.jp/kegg-bin/show_pathway?hsa04152/hsa:5521%09red Lysosome KEGG PATHWAY hsa04142 1 123 0.238279766979 0.347674493121 527 http://www.genome.jp/kegg-bin/show_pathway?hsa04142/hsa:527%09red Platelet activation KEGG PATHWAY hsa04611 1 124 0.239952579789 0.348156665873 2207 http://www.genome.jp/kegg-bin/show_pathway?hsa04611/hsa:2207%09red Osteoclast differentiation KEGG PATHWAY hsa04380 1 128 0.246607603441 0.351213697524 8600 http://www.genome.jp/kegg-bin/show_pathway?hsa04380/hsa:8600%09red Dopaminergic synapse KEGG PATHWAY hsa04728 1 131 0.251561049295 0.355355547277 5521 http://www.genome.jp/kegg-bin/show_pathway?hsa04728/hsa:5521%09red Oxidative phosphorylation KEGG PATHWAY hsa00190 1 133 0.254845451788 0.357091913292 527 http://www.genome.jp/kegg-bin/show_pathway?hsa00190/hsa:527%09red Systemic lupus erythematosus KEGG PATHWAY hsa05322 1 133 0.254845451788 0.357091913292 733 http://www.genome.jp/kegg-bin/show_pathway?hsa05322/hsa:733%09red Signaling pathways regulating pluripotency of stem cells KEGG PATHWAY hsa04550 1 140 0.266229087122 0.367121459424 130399 http://www.genome.jp/kegg-bin/show_pathway?hsa04550/hsa:130399%09red Breast cancer KEGG PATHWAY hsa05224 1 147 0.277440831069 0.376553195484 8600 http://www.genome.jp/kegg-bin/show_pathway?hsa05224/hsa:8600%09red Phospholipase D signaling pathway KEGG PATHWAY hsa04072 1 148 0.279028626869 0.376553195484 2207 http://www.genome.jp/kegg-bin/show_pathway?hsa04072/hsa:2207%09red Adrenergic signaling in cardiomyocytes KEGG PATHWAY hsa04261 1 149 0.280612974509 0.377957397837 5521 http://www.genome.jp/kegg-bin/show_pathway?hsa04261/hsa:5521%09red Phagosome KEGG PATHWAY hsa04145 1 152 0.285345402381 0.379913897806 527 http://www.genome.jp/kegg-bin/show_pathway?hsa04145/hsa:527%09red Hippo signaling pathway KEGG PATHWAY hsa04390 1 154 0.288483248729 0.383357280816 5521 http://www.genome.jp/kegg-bin/show_pathway?hsa04390/hsa:5521%09red Hepatitis C KEGG PATHWAY hsa05160 1 155 0.290047062244 0.383839390056 5521 http://www.genome.jp/kegg-bin/show_pathway?hsa05160/hsa:5521%09red Jak-STAT signaling pathway KEGG PATHWAY hsa04630 1 162 0.300899056591 0.39235430456 5777 http://www.genome.jp/kegg-bin/show_pathway?hsa04630/hsa:5777%09red Influenza A KEGG PATHWAY hsa05164 1 167 0.308549956287 0.395649851697 6352 http://www.genome.jp/kegg-bin/show_pathway?hsa05164/hsa:6352%09red Tight junction KEGG PATHWAY hsa04530 1 170 0.313100716221 0.400009187083 5521 http://www.genome.jp/kegg-bin/show_pathway?hsa04530/hsa:5521%09red NOD-like receptor signaling pathway KEGG PATHWAY hsa04621 1 178 0.325091878033 0.412148208511 6352 http://www.genome.jp/kegg-bin/show_pathway?hsa04621/hsa:6352%09red Proteoglycans in cancer KEGG PATHWAY hsa05205 1 203 0.361246698847 0.4397814482 5777 http://www.genome.jp/kegg-bin/show_pathway?hsa05205/hsa:5777%09red Human cytomegalovirus infection KEGG PATHWAY hsa05163 1 225 0.391475286461 0.464292361929 6352 http://www.genome.jp/kegg-bin/show_pathway?hsa05163/hsa:6352%09red MicroRNAs in cancer KEGG PATHWAY hsa05206 1 299 0.483144898476 0.541233938687 406955 http://www.genome.jp/kegg-bin/show_pathway?hsa05206/hsa:406955%09red Neuroactive ligand-receptor interaction KEGG PATHWAY hsa04080 1 338 0.525820528296 0.57369743668 2797 http://www.genome.jp/kegg-bin/show_pathway?hsa04080/hsa:2797%09red PI3K-Akt signaling pathway KEGG PATHWAY hsa04151 1 354 0.542303612593 0.589829437797 5521 http://www.genome.jp/kegg-bin/show_pathway?hsa04151/hsa:5521%09red Olfactory transduction KEGG PATHWAY hsa04740 1 448 0.628313172289 0.669751004204 8590 http://www.genome.jp/kegg-bin/show_pathway?hsa04740/hsa:8590%09red Herpes simplex virus 1 infection KEGG PATHWAY hsa05168 1 492 0.662878892857 0.698031561418 6352 http://www.genome.jp/kegg-bin/show_pathway?hsa05168/hsa:6352%09red -------------------- #Term Database ID Input number Background number P-Value Corrected P-Value Input Hyperlink -------------------- #Term Database ID Input number Background number P-Value Corrected P-Value Input Hyperlink carbohydrate binding Gene Ontology GO:0030246 4 44 3.86584140873e-06 0.00268675977907 79676|8987|57452|408050 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0030246 cellular anatomical entity Gene Ontology GO:0110165 19 2864 1.19768849052e-05 0.00416196750457 10841|6354|3382|220136|402778|644353|6352|402415|121601|51191|733|55502|79605|8663|1593|163115|9420|9865|2797 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0110165 positive regulation of osteoclast differentiation Gene Ontology GO:0045672 2 6 0.0001314741294 0.0256046175169 8600|6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0045672 response to external stimulus Gene Ontology GO:0009605 6 366 0.000171806360873 0.0256046175169 6354|6352|51191|733|10692|56477 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0009605 regulation of inflammatory response Gene Ontology GO:0050727 3 47 0.000184205881416 0.0256046175169 6354|8600|2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0050727 lymphocyte migration Gene Ontology GO:0072676 2 16 0.000708256265007 0.065311276852 6354|6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0072676 establishment of protein localization to extracellular region Gene Ontology GO:0035592 3 84 0.000939730602188 0.065311276852 3382|6352|130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0035592 metal ion homeostasis Gene Ontology GO:0055065 3 84 0.000939730602188 0.065311276852 8600|6352|10058 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0055065 plasma membrane protein complex Gene Ontology GO:0098797 3 89 0.00110464309994 0.0680747852108 733|5777|2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0098797 regulation of leukocyte migration Gene Ontology GO:0002685 2 23 0.00137498466725 0.0735087956721 6354|56477 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002685 transmembrane transport Gene Ontology GO:0055085 4 235 0.00191861067162 0.0809314462495 3748|1244|5777|121601 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0055085 regulation of insulin secretion Gene Ontology GO:0050796 2 28 0.0019796181097 0.0809314462495 3382|130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0050796 immune effector process Gene Ontology GO:0002252 3 113 0.00214700624 0.0828982964887 733|51191|1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002252 positive regulation of leukocyte cell-cell adhesion Gene Ontology GO:1903039 2 31 0.00239263590854 0.0840146021989 6352|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1903039 immune response Gene Ontology GO:0006955 4 251 0.00242541577436 0.0840146021989 56477|51191|5777|2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006955 leukocyte mediated immunity Gene Ontology GO:0002443 2 32 0.00253857071392 0.0840146021989 1636|2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002443 extracellular exosome Gene Ontology GO:0070062 5 445 0.00313837478848 0.0935011358162 10841|527|55521|1636|10058 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0070062 positive regulation of lymphocyte activation Gene Ontology GO:0051251 2 38 0.00349965609272 0.0972904393775 8600|6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051251 catalytic activity, acting on a protein Gene Ontology GO:0140096 5 488 0.00461439357933 0.119199988013 140686|100526835|51191|55521|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0140096 cellular response to tumor necrosis factor Gene Ontology GO:0071356 2 45 0.00480230167535 0.119199988013 6354|8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0071356 regulation of response to external stimulus Gene Ontology GO:0032101 3 156 0.00520563097946 0.121518830313 51191|8600|9865 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0032101 cytokine receptor binding Gene Ontology GO:0005126 2 49 0.00563215997836 0.121518830313 56477|6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005126 regulation of biological process Gene Ontology GO:0050789 10 1778 0.00565901256617 0.121518830313 2649|6354|100526835|140686|345222|165082|8663|163115|9420|23220 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0050789 regulation of hormone secretion Gene Ontology GO:0046883 2 50 0.00584916450755 0.121518830313 3382|130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0046883 ion transmembrane transporter activity Gene Ontology GO:0015075 3 163 0.00586414033383 0.121518830313 1244|3748|121601 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0015075 organic acid biosynthetic process Gene Ontology GO:0016053 2 51 0.00606995043388 0.121518830313 9420|1593 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0016053 cation transmembrane transport Gene Ontology GO:0098655 3 167 0.00626181034905 0.121518830313 527|5777|10058 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0098655 myeloid cell differentiation Gene Ontology GO:0030099 2 52 0.00629450056299 0.121518830313 8600|6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0030099 carboxylic acid biosynthetic process Gene Ontology GO:0046394 2 53 0.0065227977561 0.122522822716 9420|1593 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0046394 leukocyte migration Gene Ontology GO:0050900 2 56 0.00723000116276 0.132232916003 6354|6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0050900 anion transmembrane transport Gene Ontology GO:0098656 2 59 0.00797031645572 0.142035126583 81796|1244 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0098656 T cell activation Gene Ontology GO:0042110 2 66 0.00982394619844 0.144787317268 8600|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0042110 divalent inorganic cation homeostasis Gene Ontology GO:0072507 2 67 0.0101029334883 0.144787317268 56477|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0072507 regulation of cell activation Gene Ontology GO:0050865 2 68 0.0103854173282 0.144787317268 8600|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0050865 intrinsic component of membrane Gene Ontology GO:0031224 6 843 0.0109065473138 0.144787317268 57452|284723|733|1244|9865|80329 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0031224 regulation of response to stress Gene Ontology GO:0080134 3 207 0.0111277154478 0.144787317268 8600|51191|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0080134 generation of precursor metabolites and energy Gene Ontology GO:0006091 2 71 0.011253685713 0.144787317268 8987|8608 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006091 cytoplasmic vesicle membrane Gene Ontology GO:0030659 2 75 0.0124593475864 0.144787317268 527|3382 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0030659 response to isoquinoline alkaloid Gene Ontology GO:0014072 1 5 0.0130636774245 0.144787317268 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0014072 regulation of oligodendrocyte differentiation Gene Ontology GO:0048713 1 5 0.0130636774245 0.144787317268 1745 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048713 positive regulation of interleukin-10 production Gene Ontology GO:0032733 1 5 0.0130636774245 0.144787317268 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0032733 cell adhesion mediated by integrin Gene Ontology GO:0033627 1 5 0.0130636774245 0.144787317268 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0033627 regulation of heat generation Gene Ontology GO:0031650 1 5 0.0130636774245 0.144787317268 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0031650 CCR chemokine receptor binding Gene Ontology GO:0048020 1 5 0.0130636774245 0.144787317268 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048020 blood vessel remodeling Gene Ontology GO:0001974 1 5 0.0130636774245 0.144787317268 1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0001974 cellular component disassembly involved in execution phase of apoptosis Gene Ontology GO:0006921 1 5 0.0130636774245 0.144787317268 130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006921 endoribonuclease complex Gene Ontology GO:1902555 1 5 0.0130636774245 0.144787317268 79897 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1902555 cytoplasmic translational initiation Gene Ontology GO:0002183 1 5 0.0130636774245 0.144787317268 8663 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002183 negative regulation of response to stimulus Gene Ontology GO:0048585 3 220 0.0130692103495 0.144787317268 1745|6352|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048585 immune system process Gene Ontology GO:0002376 4 410 0.0131002575961 0.144787317268 56477|6354|51191|733 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002376 cellular response to organonitrogen compound Gene Ontology GO:0071417 2 79 0.0137188963473 0.144787317268 527|6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0071417 cation binding Gene Ontology GO:0043169 5 641 0.0138392845162 0.144787317268 79676|9420|84217|1593|124637 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043169 regulation of phosphorylation Gene Ontology GO:0042325 3 230 0.0146862359754 0.144787317268 6354|8600|1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0042325 positive regulation of receptor signaling pathway via STAT Gene Ontology GO:1904894 1 6 0.0152244992935 0.144787317268 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1904894 negative regulation of response to cytokine stimulus Gene Ontology GO:0060761 1 6 0.0152244992935 0.144787317268 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0060761 B cell receptor signaling pathway Gene Ontology GO:0050853 1 6 0.0152244992935 0.144787317268 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0050853 macrophage chemotaxis Gene Ontology GO:0048246 1 6 0.0152244992935 0.144787317268 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048246 positive regulation of immunoglobulin mediated immune response Gene Ontology GO:0002891 1 6 0.0152244992935 0.144787317268 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002891 cellular polysaccharide catabolic process Gene Ontology GO:0044247 1 6 0.0152244992935 0.144787317268 8987 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0044247 long-term synaptic potentiation Gene Ontology GO:0060291 1 6 0.0152244992935 0.144787317268 91683 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0060291 interleukin-10 production Gene Ontology GO:0032613 1 6 0.0152244992935 0.144787317268 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0032613 inflammatory response to antigenic stimulus Gene Ontology GO:0002437 1 6 0.0152244992935 0.144787317268 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002437 regulation of protein modification process Gene Ontology GO:0031399 3 235 0.0155353876684 0.144787317268 6354|8600|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0031399 positive regulation of cell communication Gene Ontology GO:0010647 3 236 0.0157084822913 0.144787317268 8600|91683|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0010647 ubiquitin-protein transferase activity Gene Ontology GO:0004842 2 87 0.0163956298519 0.144787317268 23220|51191 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0004842 endonuclease complex Gene Ontology GO:1905348 1 7 0.0173806457455 0.144787317268 79897 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1905348 negative regulation of lymphocyte apoptotic process Gene Ontology GO:0070229 1 7 0.0173806457455 0.144787317268 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0070229 negative regulation of G protein-coupled receptor signaling pathway Gene Ontology GO:0045744 1 7 0.0173806457455 0.144787317268 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0045744 forebrain neuron differentiation Gene Ontology GO:0021879 1 7 0.0173806457455 0.144787317268 1745 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0021879 response to activity Gene Ontology GO:0014823 1 7 0.0173806457455 0.144787317268 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0014823 phagosome maturation Gene Ontology GO:0090382 1 7 0.0173806457455 0.144787317268 527 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0090382 regulation of smooth muscle cell migration Gene Ontology GO:0014910 1 7 0.0173806457455 0.144787317268 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0014910 megakaryocyte differentiation Gene Ontology GO:0030219 1 7 0.0173806457455 0.144787317268 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0030219 signaling receptor activity Gene Ontology GO:0038023 3 246 0.0174994743173 0.144787317268 2207|8590|130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0038023 synaptic signaling Gene Ontology GO:0099536 2 95 0.0192759675113 0.146280309627 26045|91683 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0099536 positive regulation of cytokine production involved in immune response Gene Ontology GO:0002720 1 8 0.0195321267767 0.146280309627 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002720 neutrophil chemotaxis Gene Ontology GO:0030593 1 8 0.0195321267767 0.146280309627 6354 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0030593 fatty acid derivative transport Gene Ontology GO:1901571 1 8 0.0195321267767 0.146280309627 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1901571 regulation of intracellular estrogen receptor signaling pathway Gene Ontology GO:0033146 1 8 0.0195321267767 0.146280309627 9420 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0033146 chronic inflammatory response Gene Ontology GO:0002544 1 8 0.0195321267767 0.146280309627 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002544 positive regulation of organic acid transport Gene Ontology GO:0032892 1 8 0.0195321267767 0.146280309627 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0032892 cellular iron ion homeostasis Gene Ontology GO:0006879 1 8 0.0195321267767 0.146280309627 10058 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006879 chemotaxis Gene Ontology GO:0006935 2 97 0.0200269567571 0.146280309627 56477|2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006935 regulation of cell migration Gene Ontology GO:0030334 2 99 0.0207900696854 0.146280309627 56477|6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0030334 natural killer cell mediated cytotoxicity Gene Ontology GO:0042267 1 9 0.0216789523621 0.146280309627 80329 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0042267 regulation of myeloid cell apoptotic process Gene Ontology GO:0033032 1 9 0.0216789523621 0.146280309627 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0033032 mammary gland epithelial cell proliferation Gene Ontology GO:0033598 1 9 0.0216789523621 0.146280309627 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0033598 negative regulation of intracellular steroid hormone receptor signaling pathway Gene Ontology GO:0033144 1 9 0.0216789523621 0.146280309627 9420 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0033144 monocyte chemotaxis Gene Ontology GO:0002548 1 9 0.0216789523621 0.146280309627 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002548 acute-phase response Gene Ontology GO:0006953 1 9 0.0216789523621 0.146280309627 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006953 ion gated channel activity Gene Ontology GO:0022839 1 9 0.0216789523621 0.146280309627 121601 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0022839 plasma membrane organization Gene Ontology GO:0007009 1 9 0.0216789523621 0.146280309627 121601 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0007009 spliceosomal snRNP complex Gene Ontology GO:0097525 1 9 0.0216789523621 0.146280309627 8926 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0097525 regulation of cytokine production Gene Ontology GO:0001817 2 106 0.0235547458673 0.149184529158 23220|2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0001817 ATPase-coupled ion transmembrane transporter activity Gene Ontology GO:0042625 1 10 0.0238211324555 0.149184529158 527 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0042625 chemokine receptor binding Gene Ontology GO:0042379 1 10 0.0238211324555 0.149184529158 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0042379 negative regulation of peptide hormone secretion Gene Ontology GO:0090278 1 10 0.0238211324555 0.149184529158 130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0090278 positive regulation of synapse assembly Gene Ontology GO:0051965 1 10 0.0238211324555 0.149184529158 26045 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051965 Fc receptor mediated stimulatory signaling pathway Gene Ontology GO:0002431 1 10 0.0238211324555 0.149184529158 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002431 acrosomal vesicle Gene Ontology GO:0001669 1 10 0.0238211324555 0.149184529158 55521 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0001669 organelle membrane Gene Ontology GO:0031090 4 493 0.0238265938654 0.149184529158 10841|57452|1593|9420 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0031090 intrinsic component of plasma membrane Gene Ontology GO:0031226 3 283 0.0250812283428 0.154198978702 8987|80329|2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0031226 binding Gene Ontology GO:0005488 10 2247 0.0255034413982 0.154198978702 6354|220136|91683|79781|100526835|5521|8663|1244|23220|2797 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005488 negative regulation of lymphocyte proliferation Gene Ontology GO:0050672 1 11 0.0259586769901 0.154198978702 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0050672 protein kinase activator activity Gene Ontology GO:0030295 1 11 0.0259586769901 0.154198978702 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0030295 fatty acid transport Gene Ontology GO:0015908 1 11 0.0259586769901 0.154198978702 1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0015908 cellular response to alcohol Gene Ontology GO:0097306 1 11 0.0259586769901 0.154198978702 6354 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0097306 amide transport Gene Ontology GO:0042886 3 288 0.0262214311193 0.154439784982 8600|527|130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0042886 programmed cell death Gene Ontology GO:0012501 3 289 0.0264527728549 0.154493085161 5521|6352|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0012501 extracellular vesicle Gene Ontology GO:1903561 4 514 0.0271874501827 0.157448863991 5777|10841|9687|1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1903561 negative regulation of T cell activation Gene Ontology GO:0050868 1 12 0.0280915958776 0.157448863991 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0050868 response to antineoplastic agent Gene Ontology GO:0097327 1 12 0.0280915958776 0.157448863991 1244 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0097327 chemokine-mediated signaling pathway Gene Ontology GO:0070098 1 12 0.0280915958776 0.157448863991 6354 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0070098 cellular response to interleukin-1 Gene Ontology GO:0071347 1 12 0.0280915958776 0.157448863991 6354 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0071347 cell surface Gene Ontology GO:0009986 2 119 0.0290624767638 0.160059682359 1636|2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0009986 regulation of secretion by cell Gene Ontology GO:1903530 2 120 0.0295055600334 0.160059682359 3382|2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1903530 regulation of protein kinase activity Gene Ontology GO:0045859 2 121 0.0299513471859 0.160059682359 8600|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0045859 positive regulation of JUN kinase activity Gene Ontology GO:0043507 1 13 0.030219899009 0.160059682359 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043507 positive regulation of protein kinase B signaling Gene Ontology GO:0051897 1 13 0.030219899009 0.160059682359 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051897 mitochondrial envelope Gene Ontology GO:0005740 2 122 0.0303998245632 0.160059682359 5521|1593 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005740 cell-cell adhesion Gene Ontology GO:0098609 2 122 0.0303998245632 0.160059682359 8600|6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0098609 sexual reproduction Gene Ontology GO:0019953 2 126 0.0322203647493 0.162889850702 2649|55521 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0019953 multicellular organism development Gene Ontology GO:0007275 5 802 0.0322544906449 0.162889850702 9420|8600|26045|2797|55502 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0007275 regulation of signaling receptor activity Gene Ontology GO:0010469 1 14 0.0323435962545 0.162889850702 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0010469 response to vitamin Gene Ontology GO:0033273 1 14 0.0323435962545 0.162889850702 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0033273 cellular polysaccharide metabolic process Gene Ontology GO:0044264 1 14 0.0323435962545 0.162889850702 8987 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0044264 positive regulation of inflammatory response Gene Ontology GO:0050729 1 14 0.0323435962545 0.162889850702 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0050729 metabolic process Gene Ontology GO:0008152 8 1706 0.0340324051464 0.163163075605 10841|100526835|163115|284723|51191|527|9420|282808 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0008152 regulation of biological quality Gene Ontology GO:0065008 4 554 0.0343411997572 0.163163075605 56477|6352|1244|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0065008 positive regulation of lymphocyte proliferation Gene Ontology GO:0050671 1 15 0.0344626974633 0.163163075605 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0050671 regulation of cyclin-dependent protein kinase activity Gene Ontology GO:1904029 1 15 0.0344626974633 0.163163075605 51191 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1904029 neutrophil migration Gene Ontology GO:1990266 1 15 0.0344626974633 0.163163075605 6354 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1990266 regulation of adaptive immune response Gene Ontology GO:0002819 1 15 0.0344626974633 0.163163075605 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002819 exopeptidase activity Gene Ontology GO:0008238 1 15 0.0344626974633 0.163163075605 1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0008238 regulation of osteoclast differentiation Gene Ontology GO:0045670 1 15 0.0344626974633 0.163163075605 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0045670 multicellular organismal process Gene Ontology GO:0032501 6 1100 0.034510751243 0.163163075605 1636|2207|8600|8987|10692|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0032501 cellular response to cytokine stimulus Gene Ontology GO:0071345 2 132 0.0350295883261 0.164497053288 8600|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0071345 tumor necrosis factor production Gene Ontology GO:0032640 1 16 0.0365772124639 0.170611829949 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0032640 stem cell proliferation Gene Ontology GO:0072089 1 17 0.0386871510638 0.177745726105 1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0072089 response to organonitrogen compound Gene Ontology GO:0010243 2 142 0.0399136850382 0.177745726105 6352|1244 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0010243 regulation of protein localization Gene Ontology GO:0032880 2 142 0.0399136850382 0.177745726105 6352|130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0032880 positive regulation of immune system process Gene Ontology GO:0002684 2 143 0.0404155816893 0.177745726105 733|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002684 release of sequestered calcium ion into cytosol Gene Ontology GO:0051209 1 18 0.0407925230501 0.177745726105 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051209 regulation of lipid transport Gene Ontology GO:0032368 1 18 0.0407925230501 0.177745726105 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0032368 detection of external stimulus Gene Ontology GO:0009581 1 18 0.0407925230501 0.177745726105 10692 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0009581 positive regulation of viral process Gene Ontology GO:0048524 1 18 0.0407925230501 0.177745726105 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048524 regulation of developmental process Gene Ontology GO:0050793 3 344 0.0408570723226 0.177745726105 6354|8600|1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0050793 negative regulation of protein metabolic process Gene Ontology GO:0051248 2 144 0.0409198793911 0.177745726105 140686|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051248 regulation of heart rate Gene Ontology GO:0002027 1 19 0.042893338189 0.178673007584 100526835 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002027 positive regulation of endopeptidase activity Gene Ontology GO:0010950 1 19 0.042893338189 0.178673007584 130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0010950 positive regulation of cellular amide metabolic process Gene Ontology GO:0034250 1 19 0.042893338189 0.178673007584 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0034250 acid secretion Gene Ontology GO:0046717 1 19 0.042893338189 0.178673007584 1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0046717 regulation of catalytic activity Gene Ontology GO:0050790 3 351 0.0429240230493 0.178673007584 6354|51191|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0050790 carbohydrate derivative binding Gene Ontology GO:0097367 3 351 0.0429240230493 0.178673007584 6354|6352|130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0097367 catalytic activity Gene Ontology GO:0003824 6 1162 0.0431183029668 0.178673007584 57452|8600|100526835|84290|9420|23220 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0003824 integral component of membrane Gene Ontology GO:0016021 5 871 0.0433778728263 0.178673007584 165082|147685|408050|284723|733 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0016021 positive regulation of leukocyte migration Gene Ontology GO:0002687 1 20 0.0449896062261 0.178673007584 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002687 oxidoreductase activity, acting on CH-OH group of donors Gene Ontology GO:0016614 1 20 0.0449896062261 0.178673007584 8608 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0016614 organic anion transmembrane transporter activity Gene Ontology GO:0008514 1 20 0.0449896062261 0.178673007584 81796 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0008514 intracellular steroid hormone receptor signaling pathway Gene Ontology GO:0030518 1 20 0.0449896062261 0.178673007584 2649 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0030518 heme binding Gene Ontology GO:0020037 1 20 0.0449896062261 0.178673007584 10058 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0020037 regulation of response to wounding Gene Ontology GO:1903034 1 20 0.0449896062261 0.178673007584 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1903034 cellular component assembly Gene Ontology GO:0022607 3 360 0.0456575119514 0.180295288672 26045|3748|1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0022607 cellular response to radiation Gene Ontology GO:0071478 1 21 0.0470813368866 0.181061609489 10692 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0071478 positive regulation of peptidyl-tyrosine phosphorylation Gene Ontology GO:0050731 1 21 0.0470813368866 0.181061609489 1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0050731 striated muscle contraction Gene Ontology GO:0006941 1 21 0.0470813368866 0.181061609489 100526835 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006941 gland morphogenesis Gene Ontology GO:0022612 1 21 0.0470813368866 0.181061609489 9420 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0022612 export from cell Gene Ontology GO:0140352 2 156 0.0471541745575 0.181061609489 6352|2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0140352 regulation of cellular macromolecule biosynthetic process Gene Ontology GO:2000112 4 619 0.0481029154481 0.181306743064 2649|8600|8663|55502 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:2000112 monocarboxylic acid transport Gene Ontology GO:0015718 1 22 0.0491685398748 0.181306743064 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0015718 response to amino acid Gene Ontology GO:0043200 1 22 0.0491685398748 0.181306743064 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043200 regulation of cytokine-mediated signaling pathway Gene Ontology GO:0001959 1 22 0.0491685398748 0.181306743064 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0001959 cellular amino acid catabolic process Gene Ontology GO:0009063 1 22 0.0491685398748 0.181306743064 10841 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0009063 hormone activity Gene Ontology GO:0005179 1 22 0.0491685398748 0.181306743064 2797 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005179 catalytic activity, acting on a tRNA Gene Ontology GO:0140101 1 22 0.0491685398748 0.181306743064 79897 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0140101 chemical homeostasis Gene Ontology GO:0048878 2 160 0.049304999193 0.181306743064 56477|6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048878 RNA processing Gene Ontology GO:0006396 2 161 0.0498482149823 0.182339523225 8926|79897 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006396 iron ion binding Gene Ontology GO:0005506 1 23 0.0512512248748 0.18266462199 79676 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005506 calcium ion transmembrane import into cytosol Gene Ontology GO:0097553 1 23 0.0512512248748 0.18266462199 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0097553 regulation of viral life cycle Gene Ontology GO:1903900 1 23 0.0512512248748 0.18266462199 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1903900 ribonucleoprotein complex subunit organization Gene Ontology GO:0071826 1 24 0.0533294015501 0.184397681977 8663 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0071826 endopeptidase regulator activity Gene Ontology GO:0061135 1 24 0.0533294015501 0.184397681977 140686 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0061135 primary active transmembrane transporter activity Gene Ontology GO:0015399 1 24 0.0533294015501 0.184397681977 10058 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0015399 carbohydrate catabolic process Gene Ontology GO:0016052 1 24 0.0533294015501 0.184397681977 8987 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0016052 insulin receptor signaling pathway Gene Ontology GO:0008286 1 24 0.0533294015501 0.184397681977 527 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0008286 antigen processing and presentation of peptide antigen Gene Ontology GO:0048002 1 25 0.0554030795439 0.190619506351 1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048002 endocytic vesicle membrane Gene Ontology GO:0030666 1 26 0.0574722684787 0.196764663018 527 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0030666 positive regulation of NF-kappaB transcription factor activity Gene Ontology GO:0051092 1 27 0.0595369779571 0.198933652308 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051092 vacuole organization Gene Ontology GO:0007033 1 27 0.0595369779571 0.198933652308 527 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0007033 positive regulation of stress-activated protein kinase signaling cascade Gene Ontology GO:0070304 1 27 0.0595369779571 0.198933652308 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0070304 negative regulation of establishment of protein localization Gene Ontology GO:1904950 1 27 0.0595369779571 0.198933652308 130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1904950 antigen processing and presentation of exogenous antigen Gene Ontology GO:0019884 1 28 0.061597217561 0.200047038341 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0019884 cell-matrix adhesion Gene Ontology GO:0007160 1 28 0.061597217561 0.200047038341 56477 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0007160 carboxylic acid transmembrane transport Gene Ontology GO:1905039 1 28 0.061597217561 0.200047038341 1244 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1905039 negative regulation of secretion by cell Gene Ontology GO:1903531 1 28 0.061597217561 0.200047038341 130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1903531 transferase activity, transferring one-carbon groups Gene Ontology GO:0016741 1 28 0.061597217561 0.200047038341 10841 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0016741 negative regulation of cell motility Gene Ontology GO:2000146 1 29 0.0636529968525 0.202003802797 56477 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:2000146 positive regulation of ERK1 and ERK2 cascade Gene Ontology GO:0070374 1 29 0.0636529968525 0.202003802797 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0070374 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Gene Ontology GO:0002822 1 29 0.0636529968525 0.202003802797 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002822 cellular response to insulin stimulus Gene Ontology GO:0032869 1 29 0.0636529968525 0.202003802797 527 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0032869 plasma membrane signaling receptor complex Gene Ontology GO:0098802 1 29 0.0636529968525 0.202003802797 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0098802 catabolic process Gene Ontology GO:0009056 3 417 0.0648973591131 0.203840228518 8987|1636|387104 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0009056 exocytic vesicle Gene Ontology GO:0070382 1 30 0.065704325373 0.203840228518 3382 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0070382 organic substance transport Gene Ontology GO:0071702 3 421 0.0663685124458 0.203840228518 8600|2207|121601 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0071702 insulin secretion Gene Ontology GO:0030073 1 31 0.0677512126441 0.203840228518 3382 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0030073 lipase activity Gene Ontology GO:0016298 1 31 0.0677512126441 0.203840228518 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0016298 regulation of response to cytokine stimulus Gene Ontology GO:0060759 1 31 0.0677512126441 0.203840228518 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0060759 lymphocyte mediated immunity Gene Ontology GO:0002449 1 31 0.0677512126441 0.203840228518 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002449 cellular response to peptide hormone stimulus Gene Ontology GO:0071375 1 31 0.0677512126441 0.203840228518 527 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0071375 receptor metabolic process Gene Ontology GO:0043112 1 32 0.069793668167 0.204602592169 26045 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043112 protein kinase regulator activity Gene Ontology GO:0019887 1 32 0.069793668167 0.204602592169 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0019887 cell junction assembly Gene Ontology GO:0034329 1 32 0.069793668167 0.204602592169 1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0034329 neuron apoptotic process Gene Ontology GO:0051402 1 32 0.069793668167 0.204602592169 1745 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051402 leukocyte proliferation Gene Ontology GO:0070661 1 32 0.069793668167 0.204602592169 1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0070661 macromolecule glycosylation Gene Ontology GO:0043413 1 32 0.069793668167 0.204602592169 57452 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043413 localization of cell Gene Ontology GO:0051674 2 197 0.0707660359572 0.204602592169 56477|2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051674 voltage-gated ion channel activity Gene Ontology GO:0005244 1 33 0.0718317014232 0.204602592169 3748 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005244 outer membrane Gene Ontology GO:0019867 1 33 0.0718317014232 0.204602592169 10058 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0019867 inorganic anion transport Gene Ontology GO:0015698 1 33 0.0718317014232 0.204602592169 121601 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0015698 regulation of I-kappaB kinase/NF-kappaB signaling Gene Ontology GO:0043122 1 33 0.0718317014232 0.204602592169 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043122 tumor necrosis factor-mediated signaling pathway Gene Ontology GO:0033209 1 33 0.0718317014232 0.204602592169 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0033209 response to ionizing radiation Gene Ontology GO:0010212 1 33 0.0718317014232 0.204602592169 6354 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0010212 identical protein binding Gene Ontology GO:0042802 2 202 0.0738648913689 0.207839670859 2649|3382 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0042802 humoral immune response Gene Ontology GO:0006959 1 34 0.0738653218738 0.207839670859 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006959 negative regulation of protein kinase activity Gene Ontology GO:0006469 1 34 0.0738653218738 0.207839670859 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006469 response to other organism Gene Ontology GO:0051707 2 203 0.0744898770473 0.208751873177 6352|9865 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051707 protein autophosphorylation Gene Ontology GO:0046777 1 35 0.0758945389599 0.211834154928 1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0046777 phospholipase activity Gene Ontology GO:0004620 1 36 0.077919362103 0.215752815385 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0004620 mononuclear cell proliferation Gene Ontology GO:0032943 1 36 0.077919362103 0.215752815385 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0032943 extracellular region Gene Ontology GO:0005576 4 736 0.0794997668822 0.21873291925 57452|8600|6352|9687 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005576 organic acid binding Gene Ontology GO:0043177 1 37 0.0799398007043 0.21873291925 79676 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043177 regulation of leukocyte differentiation Gene Ontology GO:1902105 1 37 0.0799398007043 0.21873291925 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1902105 response to biotic stimulus Gene Ontology GO:0009607 2 214 0.0814755995664 0.220772579771 6352|51191 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0009607 modulation of chemical synaptic transmission Gene Ontology GO:0050804 1 38 0.0819558641453 0.220772579771 26045 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0050804 protein tyrosine kinase activity Gene Ontology GO:0004713 1 38 0.0819558641453 0.220772579771 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0004713 protein dephosphorylation Gene Ontology GO:0006470 1 38 0.0819558641453 0.220772579771 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006470 reproduction Gene Ontology GO:0000003 2 216 0.0827669581487 0.222096663758 2649|130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0000003 molecular transducer activity Gene Ontology GO:0060089 2 217 0.0834150169507 0.22212846679 2649|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0060089 catalytic activity, acting on RNA Gene Ontology GO:0140098 1 39 0.0839675617876 0.22212846679 79897 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0140098 regulation of stress-activated protein kinase signaling cascade Gene Ontology GO:0070302 1 39 0.0839675617876 0.22212846679 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0070302 lipid metabolic process Gene Ontology GO:0006629 2 218 0.0840646489756 0.22212846679 8608|1593 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006629 peptide hormone secretion Gene Ontology GO:0030072 1 40 0.0859749029732 0.22212846679 3382 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0030072 cell fate commitment Gene Ontology GO:0045165 1 40 0.0859749029732 0.22212846679 1745 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0045165 ubiquitin protein ligase binding Gene Ontology GO:0031625 1 40 0.0859749029732 0.22212846679 527 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0031625 regulation of cysteine-type endopeptidase activity Gene Ontology GO:2000116 1 40 0.0859749029732 0.22212846679 130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:2000116 positive regulation of T cell activation Gene Ontology GO:0050870 1 40 0.0859749029732 0.22212846679 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0050870 transmembrane receptor protein serine/threonine kinase signaling pathway Gene Ontology GO:0007178 1 40 0.0859749029732 0.22212846679 644353 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0007178 defense response to bacterium Gene Ontology GO:0042742 1 41 0.0879778970242 0.225625972073 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0042742 regulation of cysteine-type endopeptidase activity involved in apoptotic process Gene Ontology GO:0043281 1 41 0.0879778970242 0.225625972073 130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043281 protein maturation Gene Ontology GO:0051604 1 42 0.0899765532428 0.229071305902 1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051604 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Gene Ontology GO:0016818 2 227 0.0899805273545 0.229071305902 6354|6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0016818 lipid transport Gene Ontology GO:0006869 1 43 0.0919708809119 0.232394370319 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006869 amide binding Gene Ontology GO:0033218 1 44 0.0939608892946 0.232394370319 10841 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0033218 protein homooligomerization Gene Ontology GO:0051260 1 44 0.0939608892946 0.232394370319 3748 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051260 homeostasis of number of cells Gene Ontology GO:0048872 1 44 0.0939608892946 0.232394370319 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048872 peptidyl-tyrosine modification Gene Ontology GO:0018212 1 44 0.0939608892946 0.232394370319 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0018212 regulation of binding Gene Ontology GO:0051098 1 44 0.0939608892946 0.232394370319 3382 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051098 neurotransmitter transport Gene Ontology GO:0006836 1 44 0.0939608892946 0.232394370319 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006836 positive regulation of leukocyte activation Gene Ontology GO:0002696 1 45 0.0959465876344 0.235628545604 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002696 activation of protein kinase activity Gene Ontology GO:0032147 1 45 0.0959465876344 0.235628545604 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0032147 regulation of leukocyte cell-cell adhesion Gene Ontology GO:1903037 1 46 0.0979279851552 0.237142681822 56477 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1903037 G protein-coupled receptor binding Gene Ontology GO:0001664 1 46 0.0979279851552 0.237142681822 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0001664 cellular response to abiotic stimulus Gene Ontology GO:0071214 1 46 0.0979279851552 0.237142681822 10692 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0071214 coagulation Gene Ontology GO:0050817 1 46 0.0979279851552 0.237142681822 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0050817 peptidyl-tyrosine phosphorylation Gene Ontology GO:0018108 1 47 0.0999050910616 0.240094569961 1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0018108 cell junction organization Gene Ontology GO:0034330 1 47 0.0999050910616 0.240094569961 1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0034330 animal organ development Gene Ontology GO:0048513 3 504 0.100183345739 0.240094569961 9420|5777|2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048513 regulation of phosphorus metabolic process Gene Ontology GO:0051174 2 243 0.100788692519 0.240715262203 6354|6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051174 MAP kinase activity Gene Ontology GO:0004707 1 48 0.101877914539 0.24165580411 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0004707 DNA-binding transcription factor activity, RNA polymerase II-specific Gene Ontology GO:0000981 1 49 0.103846464752 0.24431385993 55502 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0000981 cell periphery Gene Ontology GO:0071944 4 812 0.104235737883 0.24431385993 8600|3748|5777|130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0071944 positive regulation of molecular function Gene Ontology GO:0044093 2 250 0.105626490482 0.24431385993 6352|130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0044093 hydrolase activity, acting on acid phosphorus-nitrogen bonds Gene Ontology GO:0016825 1 50 0.105810750847 0.24431385993 140686 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0016825 positive regulation of response to biotic stimulus Gene Ontology GO:0002833 1 50 0.105810750847 0.24431385993 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002833 serine-type peptidase activity Gene Ontology GO:0008236 1 51 0.107770781952 0.24557604412 140686 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0008236 presynapse Gene Ontology GO:0098793 1 51 0.107770781952 0.24557604412 3382 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0098793 transport vesicle Gene Ontology GO:0030133 1 51 0.107770781952 0.24557604412 91683 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0030133 lymphocyte differentiation Gene Ontology GO:0030098 1 51 0.107770781952 0.24557604412 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0030098 regulation of cell population proliferation Gene Ontology GO:0042127 2 255 0.109120266637 0.2467960006 1636|130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0042127 cellular response to peptide Gene Ontology GO:1901653 1 52 0.109726567173 0.2467960006 527 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1901653 response to peptide hormone Gene Ontology GO:0043434 1 52 0.109726567173 0.2467960006 527 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043434 multicellular organismal homeostasis Gene Ontology GO:0048871 1 52 0.109726567173 0.2467960006 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048871 secretory granule Gene Ontology GO:0030141 1 53 0.1116781156 0.247185638032 3382 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0030141 cell-substrate adhesion Gene Ontology GO:0031589 1 53 0.1116781156 0.247185638032 56477 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0031589 negative regulation of protein phosphorylation Gene Ontology GO:0001933 1 53 0.1116781156 0.247185638032 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0001933 positive regulation of innate immune response Gene Ontology GO:0045089 1 53 0.1116781156 0.247185638032 9865 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0045089 hemostasis Gene Ontology GO:0007599 1 53 0.1116781156 0.247185638032 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0007599 intracellular vesicle Gene Ontology GO:0097708 2 261 0.113353110808 0.249115704193 527|1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0097708 immune response-activating cell surface receptor signaling pathway Gene Ontology GO:0002429 1 54 0.113625436301 0.249115704193 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002429 anatomical structure homeostasis Gene Ontology GO:0060249 1 54 0.113625436301 0.249115704193 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0060249 adaptive immune response Gene Ontology GO:0002250 1 55 0.115568538326 0.251787254346 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002250 epithelial cell proliferation Gene Ontology GO:0050673 1 55 0.115568538326 0.251787254346 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0050673 positive regulation of biological process Gene Ontology GO:0048518 4 845 0.11596043341 0.251851566313 2649|26045|1636|644353 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048518 positive regulation of neuron differentiation Gene Ontology GO:0045666 1 56 0.117507430706 0.253626286771 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0045666 negative regulation of immune system process Gene Ontology GO:0002683 1 56 0.117507430706 0.253626286771 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002683 side of membrane Gene Ontology GO:0098552 1 57 0.119442122452 0.254638880687 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0098552 muscle system process Gene Ontology GO:0003012 1 57 0.119442122452 0.254638880687 100526835 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0003012 regulation of MAP kinase activity Gene Ontology GO:0043405 1 57 0.119442122452 0.254638880687 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043405 positive regulation of cell development Gene Ontology GO:0010720 1 57 0.119442122452 0.254638880687 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0010720 exocytosis Gene Ontology GO:0006887 1 58 0.121372622557 0.257176745968 91683 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006887 phospholipid binding Gene Ontology GO:0005543 1 58 0.121372622557 0.257176745968 91683 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005543 positive regulation of cell activation Gene Ontology GO:0050867 1 59 0.123298939996 0.259675040294 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0050867 regulation of endopeptidase activity Gene Ontology GO:0052548 1 59 0.123298939996 0.259675040294 140686 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0052548 ion transport Gene Ontology GO:0006811 2 276 0.124116152436 0.260606422788 527|3748 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006811 transporter complex Gene Ontology GO:1990351 1 60 0.125221083721 0.260653830548 3748 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1990351 response to oxygen-containing compound Gene Ontology GO:1901700 2 278 0.125569685906 0.260653830548 6354|6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1901700 regulation of peptidase activity Gene Ontology GO:0052547 1 61 0.12713906267 0.260653830548 130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0052547 response to peptide Gene Ontology GO:1901652 1 61 0.12713906267 0.260653830548 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1901652 negative regulation of transport Gene Ontology GO:0051051 1 61 0.12713906267 0.260653830548 130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051051 organelle subcompartment Gene Ontology GO:0031984 1 61 0.12713906267 0.260653830548 3382 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0031984 vesicle membrane Gene Ontology GO:0012506 1 61 0.12713906267 0.260653830548 527 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0012506 regulation of multicellular organismal development Gene Ontology GO:2000026 2 282 0.128489112824 0.261876637573 8600|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:2000026 regulation of intracellular signal transduction Gene Ontology GO:1902531 2 282 0.128489112824 0.261876637573 6354|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1902531 positive regulation of signal transduction Gene Ontology GO:0009967 2 284 0.129954881034 0.262302537493 8600|6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0009967 peptide transport Gene Ontology GO:0015833 2 284 0.129954881034 0.262302537493 3382|6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0015833 spermatogenesis Gene Ontology GO:0007283 1 63 0.130962561885 0.262302537493 2649 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0007283 mitochondrial matrix Gene Ontology GO:0005759 1 63 0.130962561885 0.262302537493 1593 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005759 reproductive structure development Gene Ontology GO:0048608 1 63 0.130962561885 0.262302537493 9420 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048608 cellular amino acid metabolic process Gene Ontology GO:0006520 1 64 0.132868099928 0.262339004119 10841 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006520 nucleoside binding Gene Ontology GO:0001882 1 64 0.132868099928 0.262339004119 282808 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0001882 cellular metal ion homeostasis Gene Ontology GO:0006875 1 64 0.132868099928 0.262339004119 10058 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006875 monovalent inorganic cation transmembrane transporter activity Gene Ontology GO:0015077 1 64 0.132868099928 0.262339004119 3748 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0015077 response to oxidative stress Gene Ontology GO:0006979 1 64 0.132868099928 0.262339004119 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006979 regulation of ion transmembrane transport Gene Ontology GO:0034765 1 65 0.134769508748 0.263844531211 3748 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0034765 regulation of protein secretion Gene Ontology GO:0050708 1 65 0.134769508748 0.263844531211 130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0050708 receptor regulator activity Gene Ontology GO:0030545 1 65 0.134769508748 0.263844531211 6354 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0030545 RNA polymerase II cis-regulatory region sequence-specific DNA binding Gene Ontology GO:0000978 1 66 0.136666797187 0.264577782855 2649 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0000978 regulation of vesicle-mediated transport Gene Ontology GO:0060627 1 66 0.136666797187 0.264577782855 26045 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0060627 establishment of localization in cell Gene Ontology GO:0051649 1 66 0.136666797187 0.264577782855 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051649 receptor ligand activity Gene Ontology GO:0048018 1 66 0.136666797187 0.264577782855 2797 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048018 olfactory receptor activity Gene Ontology GO:0004984 1 67 0.138559974067 0.265287002691 8590 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0004984 GTP binding Gene Ontology GO:0005525 1 67 0.138559974067 0.265287002691 282808 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005525 positive regulation of nervous system development Gene Ontology GO:0051962 1 67 0.138559974067 0.265287002691 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051962 organic substance catabolic process Gene Ontology GO:1901575 2 297 0.139576022702 0.266498175214 10841|1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1901575 regulation of peptide secretion Gene Ontology GO:0002791 1 68 0.140449048194 0.26669969534 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002791 response to radiation Gene Ontology GO:0009314 1 69 0.142334028351 0.268521277381 10692 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0009314 organonitrogen compound biosynthetic process Gene Ontology GO:1901566 2 301 0.142567412019 0.268521277381 8663|57452 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1901566 RNA splicing Gene Ontology GO:0008380 1 71 0.146091741809 0.273675904468 8926 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0008380 cellular component organization or biogenesis Gene Ontology GO:0071840 4 929 0.148244576251 0.275388794291 6352|3748|5777|121601 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0071840 purine ribonucleoside triphosphate binding Gene Ontology GO:0035639 2 309 0.148591076056 0.275388794291 130399|10058 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0035639 negative regulation of phosphorylation Gene Ontology GO:0042326 1 74 0.151697825804 0.27671913106 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0042326 regulation of leukocyte activation Gene Ontology GO:0002694 1 74 0.151697825804 0.27671913106 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002694 cell-cell signaling by wnt Gene Ontology GO:0198738 1 74 0.151697825804 0.27671913106 527 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0198738 ribonucleoside binding Gene Ontology GO:0032549 1 74 0.151697825804 0.27671913106 282808 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0032549 cytoplasm Gene Ontology GO:0005737 6 1641 0.152185282686 0.276881600698 284723|5521|8987|100526835|84290|56477 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005737 signal transduction Gene Ontology GO:0007165 4 940 0.152711986892 0.277114440967 2649|8600|527|9865 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0007165 leukocyte differentiation Gene Ontology GO:0002521 1 75 0.153558425608 0.277924754681 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002521 negative regulation of protein modification process Gene Ontology GO:0031400 1 76 0.155414992424 0.279104443759 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0031400 organic anion transport Gene Ontology GO:0015711 1 76 0.155414992424 0.279104443759 121601 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0015711 regulation of RNA biosynthetic process Gene Ontology GO:2001141 3 621 0.156939871921 0.280979271847 163115|8600|55502 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:2001141 positive regulation of multi-organism process Gene Ontology GO:0043902 1 77 0.15726753489 0.280979271847 9865 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043902 secretory vesicle Gene Ontology GO:0099503 1 79 0.160960581233 0.284650391747 55521 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0099503 ribonucleoprotein complex Gene Ontology GO:1990904 1 79 0.160960581233 0.284650391747 8663 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1990904 endomembrane system Gene Ontology GO:0012505 3 633 0.163248166478 0.285984445074 8608|1636|10058 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0012505 peptide secretion Gene Ontology GO:0002790 1 81 0.164637633374 0.285984445074 130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002790 protein localization to extracellular region Gene Ontology GO:0071692 1 81 0.164637633374 0.285984445074 130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0071692 positive regulation of response to external stimulus Gene Ontology GO:0032103 1 81 0.164637633374 0.285984445074 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0032103 ubiquitin-like protein transferase activity Gene Ontology GO:0019787 1 81 0.164637633374 0.285984445074 55521 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0019787 cell death Gene Ontology GO:0008219 2 330 0.164639027572 0.285984445074 5521|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0008219 protein-containing complex Gene Ontology GO:0032991 3 639 0.166431113879 0.285984445074 733|9865|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0032991 divalent inorganic cation transport Gene Ontology GO:0072511 1 82 0.166470183021 0.285984445074 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0072511 organelle inner membrane Gene Ontology GO:0019866 1 82 0.166470183021 0.285984445074 284723 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0019866 posttranscriptional regulation of gene expression Gene Ontology GO:0010608 1 82 0.166470183021 0.285984445074 8663 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0010608 cell population proliferation Gene Ontology GO:0008283 2 333 0.166956865354 0.285984445074 6352|1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0008283 lytic vacuole Gene Ontology GO:0000323 1 83 0.168298759763 0.285984445074 1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0000323 cellular ion homeostasis Gene Ontology GO:0006873 1 83 0.168298759763 0.285984445074 6354 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006873 translation Gene Ontology GO:0006412 1 83 0.168298759763 0.285984445074 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006412 negative regulation of phosphorus metabolic process Gene Ontology GO:0010563 1 83 0.168298759763 0.285984445074 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0010563 cofactor binding Gene Ontology GO:0048037 1 84 0.170123372111 0.28837986248 1593 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048037 adherens junction Gene Ontology GO:0005912 1 86 0.173760737578 0.292622512714 527 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005912 nervous system development Gene Ontology GO:0007399 2 342 0.173944406958 0.292622512714 55502|6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0007399 organelle Gene Ontology GO:0043226 7 2086 0.174091364476 0.292622512714 2649|55502|1636|147685|8987|1593|282808 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043226 blood circulation Gene Ontology GO:0008015 1 87 0.175573507628 0.292622512714 1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0008015 wound healing Gene Ontology GO:0042060 1 87 0.175573507628 0.292622512714 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0042060 mitochondrial inner membrane Gene Ontology GO:0005743 1 87 0.175573507628 0.292622512714 284723 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005743 positive regulation of transferase activity Gene Ontology GO:0051347 1 87 0.175573507628 0.292622512714 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051347 anterograde trans-synaptic signaling Gene Ontology GO:0098916 1 88 0.177382347149 0.294226088946 91683 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0098916 cell cycle phase transition Gene Ontology GO:0044770 1 88 0.177382347149 0.294226088946 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0044770 autophagy Gene Ontology GO:0006914 1 89 0.179187264559 0.295807954558 8987 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006914 membrane organization Gene Ontology GO:0061024 1 90 0.180988268264 0.295969050455 91683 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0061024 protein complex oligomerization Gene Ontology GO:0051259 1 90 0.180988268264 0.295969050455 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051259 RNA polymerase II regulatory region DNA binding Gene Ontology GO:0001012 1 90 0.180988268264 0.295969050455 55502 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0001012 positive regulation of kinase activity Gene Ontology GO:0033674 1 91 0.182785366648 0.297507798174 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0033674 transmembrane receptor protein tyrosine kinase signaling pathway Gene Ontology GO:0007169 1 92 0.184578568079 0.299025885349 527 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0007169 organic hydroxy compound metabolic process Gene Ontology GO:1901615 1 92 0.184578568079 0.299025885349 1593 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1901615 regulation of cellular component biogenesis Gene Ontology GO:0044087 1 93 0.186367880907 0.299827956552 26045 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0044087 protein kinase binding Gene Ontology GO:0019901 1 94 0.188153313465 0.301305421332 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0019901 Wnt signaling pathway Gene Ontology GO:0016055 1 96 0.19171257101 0.305596873514 527 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0016055 cellular response to organic substance Gene Ontology GO:0071310 2 373 0.198348657468 0.315423508744 2649|8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0071310 blood vessel development Gene Ontology GO:0001568 1 102 0.202298078268 0.318814431738 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0001568 protein-containing complex binding Gene Ontology GO:0044877 1 102 0.202298078268 0.318814431738 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0044877 ion homeostasis Gene Ontology GO:0050801 1 102 0.202298078268 0.318814431738 1244 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0050801 positive regulation of programmed cell death Gene Ontology GO:0043068 1 104 0.205796044719 0.32141180018 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043068 membrane Gene Ontology GO:0016020 5 1443 0.211021188967 0.327365460562 5521|81796|5777|1636|387104 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0016020 regulation of protein metabolic process Gene Ontology GO:0051246 2 390 0.21190778072 0.328008702895 6354|8663 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051246 cellular response to hormone stimulus Gene Ontology GO:0032870 1 109 0.214474781715 0.330509918607 2649 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0032870 cellular chemical homeostasis Gene Ontology GO:0055082 1 109 0.214474781715 0.330509918607 527 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0055082 regulation of MAPK cascade Gene Ontology GO:0043408 1 110 0.216199248864 0.332430260975 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043408 mitochondrial membrane Gene Ontology GO:0031966 1 111 0.217919974724 0.333599961307 10058 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0031966 process utilizing autophagic mechanism Gene Ontology GO:0061919 1 111 0.217919974724 0.333599961307 8987 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0061919 cardiovascular system development Gene Ontology GO:0072358 1 112 0.219636967315 0.334021208499 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0072358 gamete generation Gene Ontology GO:0007276 1 112 0.219636967315 0.334021208499 1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0007276 amide biosynthetic process Gene Ontology GO:0043604 1 113 0.221350234641 0.335439959441 284723 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043604 negative regulation of metabolic process Gene Ontology GO:0009892 2 402 0.221535167458 0.335439959441 2649|55502 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0009892 cellular component biogenesis Gene Ontology GO:0044085 2 405 0.223948064009 0.338121449502 8600|1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0044085 regulation of GTPase activity Gene Ontology GO:0043087 1 115 0.224765625425 0.338121449502 6354 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043087 lipid binding Gene Ontology GO:0008289 1 115 0.224765625425 0.338121449502 733 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0008289 cellular response to growth factor stimulus Gene Ontology GO:0071363 1 116 0.226467764805 0.338836573679 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0071363 tube morphogenesis Gene Ontology GO:0035239 1 116 0.226467764805 0.338836573679 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0035239 immune system development Gene Ontology GO:0002520 1 117 0.228166210765 0.338836573679 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002520 regulation of secretion Gene Ontology GO:0051046 1 117 0.228166210765 0.338836573679 91683 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051046 positive regulation of GTPase activity Gene Ontology GO:0043547 1 117 0.228166210765 0.338836573679 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043547 regulation of nervous system development Gene Ontology GO:0051960 1 117 0.228166210765 0.338836573679 26045 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051960 peptide metabolic process Gene Ontology GO:0006518 1 119 0.231552054081 0.343131508713 8663 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006518 regulation of defense response Gene Ontology GO:0031347 1 120 0.233239467225 0.344164394313 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0031347 hematopoietic or lymphoid organ development Gene Ontology GO:0048534 1 121 0.234923218524 0.34518316464 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048534 oxidoreductase activity Gene Ontology GO:0016491 1 121 0.234923218524 0.34518316464 8608 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0016491 regulation of cellular component movement Gene Ontology GO:0051270 1 122 0.236603315831 0.346918363929 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051270 negative regulation of transcription by RNA polymerase II Gene Ontology GO:0000122 1 123 0.238279766979 0.347674493121 55502 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0000122 positive regulation of cellular process Gene Ontology GO:0048522 3 768 0.238619760027 0.347674493121 8600|2207|644353 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048522 regulation of signal transduction Gene Ontology GO:0009966 2 424 0.239274474938 0.34789907967 6354|527 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0009966 somatodendritic compartment Gene Ontology GO:0036477 1 125 0.241621762063 0.349348529963 3382 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0036477 cellular response to chemical stimulus Gene Ontology GO:0070887 2 428 0.242509076921 0.349348529963 5777|2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0070887 endosome Gene Ontology GO:0005768 1 126 0.243287321586 0.349348529963 10058 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005768 regulation of multi-organism process Gene Ontology GO:0043900 1 126 0.243287321586 0.349348529963 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043900 protein homodimerization activity Gene Ontology GO:0042803 1 126 0.243287321586 0.349348529963 2649 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0042803 double-stranded DNA binding Gene Ontology GO:0003690 1 127 0.244949266128 0.350287530779 55502 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0003690 positive regulation of cell differentiation Gene Ontology GO:0045597 1 127 0.244949266128 0.350287530779 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0045597 synapse Gene Ontology GO:0045202 1 128 0.246607603441 0.351213697524 91683 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0045202 innate immune response Gene Ontology GO:0045087 1 129 0.248262341263 0.352847294843 51191 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0045087 regulatory region nucleic acid binding Gene Ontology GO:0001067 1 130 0.249913487313 0.35374719691 55502 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0001067 mitotic cell cycle Gene Ontology GO:0000278 1 130 0.249913487313 0.35374719691 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0000278 inorganic ion transmembrane transport Gene Ontology GO:0098660 1 132 0.253205034897 0.356952331142 121601 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0098660 positive regulation of phosphate metabolic process Gene Ontology GO:0045937 1 133 0.254845451788 0.357091913292 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0045937 metal ion transport Gene Ontology GO:0030001 1 135 0.258115610045 0.36094637622 3748 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0030001 positive regulation of hydrolase activity Gene Ontology GO:0051345 1 136 0.259745366671 0.362496043849 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051345 calcium ion binding Gene Ontology GO:0005509 1 137 0.26137158511 0.364034572448 84290 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005509 anion binding Gene Ontology GO:0043168 2 454 0.263573599116 0.365636030709 10841|100526835 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043168 positive regulation of macromolecule metabolic process Gene Ontology GO:0010604 2 454 0.263573599116 0.365636030709 2649|644353 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0010604 endopeptidase activity Gene Ontology GO:0004175 1 139 0.264613437769 0.366347289342 140686 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0004175 primary metabolic process Gene Ontology GO:0044238 5 1578 0.265760862779 0.367121459424 140686|284723|1636|1593|1745 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0044238 regulation of cellular catabolic process Gene Ontology GO:0031329 1 141 0.26784122855 0.368613175926 387104 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0031329 positive regulation of cellular metabolic process Gene Ontology GO:0031325 2 461 0.26925061417 0.369820507605 1636|130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0031325 multicellular organismal reproductive process Gene Ontology GO:0048609 1 143 0.271055017725 0.371564570649 2649 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048609 transcription regulatory region DNA binding Gene Ontology GO:0044212 1 144 0.272656680475 0.373024395532 55502 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0044212 phosphate-containing compound metabolic process Gene Ontology GO:0006796 2 468 0.274927491197 0.374750653635 100526835|130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006796 regulation of cellular process Gene Ontology GO:0050794 5 1600 0.274996882524 0.374750653635 9420|6354|2797|5777|2649 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0050794 secretion by cell Gene Ontology GO:0032940 1 147 0.277440831069 0.376553195484 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0032940 negative regulation of multicellular organismal process Gene Ontology GO:0051241 1 148 0.279028626869 0.376553195484 1745 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051241 peptidase activity, acting on L-amino acid peptides Gene Ontology GO:0070011 1 148 0.279028626869 0.376553195484 1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0070011 signal transduction by protein phosphorylation Gene Ontology GO:0023014 1 150 0.282193881388 0.379351542678 130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0023014 regulation of cell communication Gene Ontology GO:0010646 2 478 0.283034513618 0.379747079082 9420|6354 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0010646 organic cyclic compound binding Gene Ontology GO:0097159 3 845 0.284018909886 0.379913897806 1745|8926|79781 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0097159 nuclear outer membrane-endoplasmic reticulum membrane network Gene Ontology GO:0042175 1 152 0.285345402381 0.379913897806 10841 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0042175 protein modification by small protein conjugation Gene Ontology GO:0032446 1 152 0.285345402381 0.379913897806 23220 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0032446 animal organ morphogenesis Gene Ontology GO:0009887 1 155 0.290047062244 0.383839390056 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0009887 multi-organism reproductive process Gene Ontology GO:0044703 1 156 0.291607479064 0.383839390056 55521 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0044703 response to nitrogen compound Gene Ontology GO:1901698 1 156 0.291607479064 0.383839390056 130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1901698 regulation of anatomical structure morphogenesis Gene Ontology GO:0022603 1 156 0.291607479064 0.383839390056 6354 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0022603 cellular component morphogenesis Gene Ontology GO:0032989 1 157 0.293164506482 0.385159417778 6354 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0032989 tube development Gene Ontology GO:0035295 1 159 0.296268422189 0.387771287046 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0035295 negative regulation of apoptotic process Gene Ontology GO:0043066 1 159 0.296268422189 0.387771287046 1745 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043066 epithelium development Gene Ontology GO:0060429 1 161 0.299358867378 0.391079723361 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0060429 positive regulation of phosphorus metabolic process Gene Ontology GO:0010562 1 163 0.302435899817 0.392884019389 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0010562 response to drug Gene Ontology GO:0042493 1 163 0.302435899817 0.392884019389 79897 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0042493 cellular process Gene Ontology GO:0009987 7 2484 0.303543855668 0.393587648674 10841|57452|3748|5521|1244|387104|8590 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0009987 cellular macromolecule metabolic process Gene Ontology GO:0044260 4 1269 0.304226282906 0.393737926666 140686|23220|51191|6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0044260 organic substance metabolic process Gene Ontology GO:0071704 5 1671 0.305248677009 0.393918749599 8663|10841|10692|79897|1593 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0071704 organelle envelope Gene Ontology GO:0031967 1 165 0.305499577027 0.393918749599 5521 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0031967 positive regulation of transport Gene Ontology GO:0051050 1 166 0.307026425331 0.395154380749 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051050 cellular amide metabolic process Gene Ontology GO:0043603 1 167 0.308549956287 0.395649851697 1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043603 peptidase activity Gene Ontology GO:0008233 1 169 0.311587094633 0.398808528121 140686 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0008233 secretion Gene Ontology GO:0046903 1 175 0.320619630924 0.40886356604 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0046903 protein metabolic process Gene Ontology GO:0019538 3 911 0.323529604275 0.411160946893 84290|5777|130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0019538 cell junction Gene Ontology GO:0030054 1 177 0.323604371152 0.411160946893 3382 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0030054 cellular metabolic process Gene Ontology GO:0044237 5 1718 0.325567433773 0.412148208511 6352|387104|51191|100526835|10058 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0044237 zinc ion binding Gene Ontology GO:0008270 1 182 0.33100964617 0.418275825615 1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0008270 catalytic complex Gene Ontology GO:1902494 1 184 0.333949271445 0.421224580134 79897 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1902494 oxoacid metabolic process Gene Ontology GO:0043436 1 187 0.338334790672 0.42521280202 1593 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043436 negative regulation of transcription, DNA-templated Gene Ontology GO:0045892 1 187 0.338334790672 0.42521280202 55502 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0045892 positive regulation of protein modification process Gene Ontology GO:0031401 1 188 0.339790279474 0.426271198979 1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0031401 response to stimulus Gene Ontology GO:0050896 4 1343 0.341026179504 0.426553255212 6354|733|9865|79897 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0050896 positive regulation of cellular component organization Gene Ontology GO:0051130 1 189 0.341242604169 0.426553255212 26045 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051130 negative regulation of RNA biosynthetic process Gene Ontology GO:1902679 1 192 0.345580661516 0.43042752644 2649 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1902679 regulation of protein phosphorylation Gene Ontology GO:0001932 1 192 0.345580661516 0.43042752644 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0001932 cell cycle process Gene Ontology GO:0022402 1 193 0.347020397611 0.431447542647 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0022402 biosynthetic process Gene Ontology GO:0009058 3 952 0.348136500114 0.431689157559 9420|284723|6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0009058 protein dimerization activity Gene Ontology GO:0046983 1 194 0.34845700344 0.431689157559 121601 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0046983 protein kinase activity Gene Ontology GO:0004672 1 195 0.349890485728 0.431925199966 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0004672 negative regulation of cell communication Gene Ontology GO:0010648 1 195 0.349890485728 0.431925199966 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0010648 regulation of transcription, DNA-templated Gene Ontology GO:0006355 2 567 0.354522112913 0.436866788075 163115|55502 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006355 regulation of cellular metabolic process Gene Ontology GO:0031323 3 969 0.358323853854 0.439340707453 6354|55502|644353 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0031323 G protein-coupled receptor signaling pathway Gene Ontology GO:0007186 1 201 0.358426159893 0.439340707453 8590 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0007186 positive regulation of protein metabolic process Gene Ontology GO:0051247 1 201 0.358426159893 0.439340707453 130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051247 response to external biotic stimulus Gene Ontology GO:0043207 1 202 0.359837964496 0.4397814482 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043207 cell adhesion Gene Ontology GO:0007155 1 203 0.361246698847 0.4397814482 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0007155 regulation of metabolic process Gene Ontology GO:0019222 3 974 0.361316844493 0.4397814482 2649|6352|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0019222 whole membrane Gene Ontology GO:0098805 1 204 0.362652369542 0.440635309146 8987 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0098805 cellular biosynthetic process Gene Ontology GO:0044249 3 984 0.367297303478 0.445500219751 163115|1593|644353 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0044249 neurogenesis Gene Ontology GO:0022008 1 210 0.371022424654 0.448453191538 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0022008 transporter activity Gene Ontology GO:0005215 1 210 0.371022424654 0.448453191538 81796 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005215 vesicle-mediated transport Gene Ontology GO:0016192 1 212 0.373788230611 0.450909700973 26045 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0016192 regulation of response to stimulus Gene Ontology GO:0048583 2 593 0.375001161384 0.450909700973 8600|51191 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048583 hydrolase activity Gene Ontology GO:0016787 2 593 0.375001161384 0.450909700973 6354|84290 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0016787 extracellular space Gene Ontology GO:0005615 2 596 0.377348117548 0.452845726072 10841|8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005615 transition metal ion binding Gene Ontology GO:0046914 1 215 0.377914418881 0.452845726072 23220 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0046914 Golgi apparatus Gene Ontology GO:0005794 1 216 0.379283835253 0.453704415664 10841 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005794 cellular protein modification process Gene Ontology GO:0006464 2 607 0.385923130569 0.46085322293 23220|1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006464 protein-containing complex assembly Gene Ontology GO:0065003 1 223 0.388786691316 0.462926133198 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0065003 intracellular organelle Gene Ontology GO:0043229 5 1863 0.38899116804 0.462926133198 5777|5521|527|80329|345222 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043229 regulation of immune system process Gene Ontology GO:0002682 1 225 0.391475286461 0.464292361929 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002682 organonitrogen compound metabolic process Gene Ontology GO:1901564 3 1027 0.392902093062 0.465190723472 57452|23220|6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1901564 negative regulation of cellular biosynthetic process Gene Ontology GO:0031327 1 232 0.400793655297 0.473727194612 55502 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0031327 regulation of programmed cell death Gene Ontology GO:0043067 1 237 0.407363158817 0.479859992166 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043067 defense response Gene Ontology GO:0006952 1 237 0.407363158817 0.479859992166 9865 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006952 regulation of hydrolase activity Gene Ontology GO:0051336 1 239 0.40997098479 0.482114779068 6354 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051336 kinase activity Gene Ontology GO:0016301 1 241 0.412567469762 0.483418024964 51191 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0016301 protein modification process Gene Ontology GO:0036211 2 643 0.413625019409 0.483418024964 5777|1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0036211 ATP binding Gene Ontology GO:0005524 1 242 0.41386147461 0.483418024964 79781 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005524 positive regulation of multicellular organismal process Gene Ontology GO:0051240 1 242 0.41386147461 0.483418024964 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051240 regulation of cellular biosynthetic process Gene Ontology GO:0031326 2 652 0.420457265291 0.490298321103 8663|6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0031326 cell-cell signaling Gene Ontology GO:0007267 1 249 0.422840971242 0.491406590056 3382 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0007267 regulation of cell differentiation Gene Ontology GO:0045595 1 249 0.422840971242 0.491406590056 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0045595 movement of cell or subcellular component Gene Ontology GO:0006928 1 250 0.424112609113 0.491406590056 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006928 metal ion binding Gene Ontology GO:0046872 2 657 0.424235905084 0.491406590056 163115|79897 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0046872 regulation of phosphate metabolic process Gene Ontology GO:0019220 1 254 0.42917153138 0.496296529632 51191 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0019220 positive regulation of cellular biosynthetic process Gene Ontology GO:0031328 1 256 0.431684498074 0.498373299272 2649 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0031328 integral component of plasma membrane Gene Ontology GO:0005887 1 258 0.434186531483 0.500430579404 81796 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005887 mitochondrion Gene Ontology GO:0005739 1 260 0.43667767861 0.502468520918 1593 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005739 adenyl nucleotide binding Gene Ontology GO:0030554 1 262 0.43915798626 0.504487273473 130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0030554 protein-containing complex subunit organization Gene Ontology GO:0043933 1 263 0.440394089853 0.505072429782 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043933 cellular response to stimulus Gene Ontology GO:0051716 3 1113 0.443279713607 0.507544317886 2649|282808|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051716 transferase activity, transferring phosphorus-containing groups Gene Ontology GO:0016772 1 269 0.447754373237 0.511398799854 130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0016772 organic cyclic compound biosynthetic process Gene Ontology GO:1901362 2 689 0.448117797282 0.511398799854 2649|55502 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1901362 transport Gene Ontology GO:0006810 2 691 0.449592517631 0.512240655333 5777|2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006810 bounding membrane of organelle Gene Ontology GO:0098588 1 276 0.456220524481 0.518941513117 5521 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0098588 transcription regulator activity Gene Ontology GO:0140110 1 278 0.458615777591 0.520813668996 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0140110 membrane-bounded organelle Gene Ontology GO:0043227 5 2030 0.461703094071 0.523161952353 9420|284723|55502|9687|1745 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043227 positive regulation of macromolecule biosynthetic process Gene Ontology GO:0010557 1 281 0.462189120496 0.523161952353 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0010557 negative regulation of cellular process Gene Ontology GO:0048523 2 723 0.47288743541 0.534287535913 1745|26045 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048523 organelle lumen Gene Ontology GO:0043233 2 725 0.474324146074 0.534287535913 345222|1593 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043233 plasma membrane Gene Ontology GO:0005886 2 726 0.475041635938 0.534287535913 64091|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005886 ribonucleotide binding Gene Ontology GO:0032553 1 292 0.475093089488 0.534287535913 1244 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0032553 establishment of protein localization Gene Ontology GO:0045184 1 295 0.47855893176 0.537315763446 527 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0045184 RNA metabolic process Gene Ontology GO:0016070 2 738 0.48360615241 0.541233938687 79897|644353 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0016070 apoptotic process Gene Ontology GO:0006915 1 302 0.486558195131 0.543662291988 1745 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006915 protein phosphorylation Gene Ontology GO:0006468 1 305 0.489949213931 0.546572558077 1636 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006468 molecular function regulator Gene Ontology GO:0098772 1 307 0.492197587537 0.548200838683 6354 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0098772 negative regulation of gene expression Gene Ontology GO:0010629 1 309 0.494436166098 0.549813016701 2649 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0010629 positive regulation of biosynthetic process Gene Ontology GO:0009891 1 311 0.496664991781 0.551409216114 644353 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0009891 small molecule metabolic process Gene Ontology GO:0044281 1 315 0.50109355228 0.55543862653 9420 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0044281 negative regulation of nitrogen compound metabolic process Gene Ontology GO:0051172 1 316 0.502194662244 0.555772755191 140686 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051172 cytoskeleton Gene Ontology GO:0005856 1 320 0.506575137076 0.559729285005 55521 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005856 establishment of localization Gene Ontology GO:0051234 2 773 0.508096656088 0.560519326954 284723|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051234 protein binding Gene Ontology GO:0005515 4 1688 0.510093911816 0.561771319967 8926|3382|2797|5521 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005515 negative regulation of biological process Gene Ontology GO:0048519 2 777 0.510848164344 0.561771319967 1745|6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048519 nitrogen compound transport Gene Ontology GO:0071705 1 325 0.51199719546 0.562145419976 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0071705 enzyme binding Gene Ontology GO:0019899 1 330 0.517360366237 0.567137940907 527 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0019899 cellular macromolecule biosynthetic process Gene Ontology GO:0034645 2 789 0.519043262646 0.568086720534 2649|644353 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0034645 positive regulation of response to stimulus Gene Ontology GO:0048584 1 333 0.520550265856 0.568840306242 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048584 cellular nitrogen compound biosynthetic process Gene Ontology GO:0044271 2 813 0.53516282802 0.582975180993 163115|8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0044271 phosphorylation Gene Ontology GO:0016310 1 360 0.548337679629 0.594531493513 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0016310 cellular localization Gene Ontology GO:0051641 1 360 0.548337679629 0.594531493513 2207 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051641 regulation of localization Gene Ontology GO:0032879 1 366 0.554293119869 0.600052520731 91683 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0032879 protein localization Gene Ontology GO:0008104 1 367 0.555278120254 0.600183971348 130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0008104 anatomical structure morphogenesis Gene Ontology GO:0009653 1 375 0.563081066317 0.607672889891 9420 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0009653 biological regulation Gene Ontology GO:0065007 4 1832 0.575285544846 0.619881323516 2649|733|3382|9865 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0065007 DNA binding Gene Ontology GO:0003677 1 401 0.58751800153 0.63208206047 55502 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0003677 macromolecule localization Gene Ontology GO:0033036 1 418 0.602760530169 0.647478467492 527 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0033036 negative regulation of macromolecule metabolic process Gene Ontology GO:0010605 1 427 0.610603361659 0.654890951162 26045 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0010605 cellular component organization Gene Ontology GO:0016043 2 936 0.611938405274 0.655311543398 84290|3748 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0016043 heterocycle metabolic process Gene Ontology GO:0046483 2 940 0.614268729842 0.656795026524 10841|644353 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0046483 regulation of macromolecule metabolic process Gene Ontology GO:0060255 2 957 0.624055313761 0.666234167533 8663|345222 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0060255 multi-organism process Gene Ontology GO:0051704 1 456 0.634848327103 0.675507264167 5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051704 positive regulation of metabolic process Gene Ontology GO:0009893 1 457 0.635657195346 0.675507264167 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0009893 organic substance biosynthetic process Gene Ontology GO:1901576 2 990 0.642512126403 0.681749508169 57452|10058 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1901576 small molecule binding Gene Ontology GO:0036094 1 467 0.643649116576 0.681914841494 733 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0036094 cell communication Gene Ontology GO:0007154 2 1003 0.649587923068 0.687159218466 2649|26045 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0007154 cellular nitrogen compound metabolic process Gene Ontology GO:0034641 2 1017 0.657085414578 0.694033986522 10841|2649 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0034641 nitrogen compound metabolic process Gene Ontology GO:0006807 3 1541 0.662112433973 0.698031561418 23220|79897|284723 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006807 regulation of signaling Gene Ontology GO:0023051 1 495 0.665116415005 0.699328151934 130399 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0023051 cytosol Gene Ontology GO:0005829 1 531 0.690848638234 0.725286712345 51191 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005829 organelle organization Gene Ontology GO:0006996 1 548 0.702310871273 0.735791354727 6354 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006996 regulation of nucleic acid-templated transcription Gene Ontology GO:1903506 1 549 0.702971884228 0.735791354727 55502 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1903506 intracellular non-membrane-bounded organelle Gene Ontology GO:0043232 1 569 0.715891673834 0.748187538819 5521 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043232 response to stress Gene Ontology GO:0006950 1 578 0.721522863689 0.752940525922 6352 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006950 transcription, DNA-templated Gene Ontology GO:0006351 1 599 0.734236947236 0.76505948775 1745 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006351 nucleus Gene Ontology GO:0005634 2 1182 0.736148570322 0.765219728973 163115|100526835 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005634 nuclear lumen Gene Ontology GO:0031981 1 603 0.736592803861 0.765219728973 644353 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0031981 non-membrane-bounded organelle Gene Ontology GO:0043228 1 606 0.738346141558 0.765896370721 10841 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043228 regulation of macromolecule biosynthetic process Gene Ontology GO:0010556 1 623 0.748066038675 0.774822499075 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0010556 macromolecule modification Gene Ontology GO:0043412 1 652 0.763830195661 0.78997319343 6354 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043412 vesicle Gene Ontology GO:0031982 1 667 0.771597428905 0.796547942378 91683 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0031982 regulation of biosynthetic process Gene Ontology GO:0009889 1 670 0.773120306751 0.796547942378 8663 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0009889 regulation of gene expression Gene Ontology GO:0010468 1 671 0.773625699432 0.796547942378 8663 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0010468 response to chemical Gene Ontology GO:0042221 1 676 0.776136022357 0.797950496358 644353 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0042221 membrane-enclosed lumen Gene Ontology GO:0031974 1 697 0.78638237973 0.807290626163 2649 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0031974 heterocycle biosynthetic process Gene Ontology GO:0018130 1 707 0.791097319065 0.810933092552 55502 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0018130 intracellular organelle lumen Gene Ontology GO:0070013 1 712 0.793416072742 0.811858563339 79897 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0070013 nucleobase-containing compound biosynthetic process Gene Ontology GO:0034654 1 714 0.794336436073 0.811858563339 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0034654 cellular protein metabolic process Gene Ontology GO:0044267 1 726 0.79977413148 0.816215890424 100526835 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0044267 macromolecule metabolic process Gene Ontology GO:0043170 2 1440 0.828815657564 0.844614196491 10692|5777 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043170 nucleic acid metabolic process Gene Ontology GO:0090304 1 811 0.8344287104 0.848599343615 79897 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0090304 heterocyclic compound binding Gene Ontology GO:1901363 1 813 0.835168274868 0.848599343615 282808 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1901363 regulation of primary metabolic process Gene Ontology GO:0080090 1 823 0.838817409824 0.851062919457 2649 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0080090 gene expression Gene Ontology GO:0010467 1 834 0.842739290315 0.853795636689 2649 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0010467 localization Gene Ontology GO:0051179 1 896 0.863143657348 0.873160712117 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051179 regulation of nitrogen compound metabolic process Gene Ontology GO:0051171 1 900 0.864366287679 0.873160712117 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0051171 intracellular membrane-bounded organelle Gene Ontology GO:0043231 2 1606 0.871984224888 0.877838884979 8608|57452 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043231 intracellular Gene Ontology GO:0005622 3 2228 0.873082831327 0.877838884979 163115|284723|10058 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005622 developmental process Gene Ontology GO:0032502 1 932 0.873766513096 0.877838884979 10058 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0032502 nucleobase-containing compound metabolic process Gene Ontology GO:0006139 1 933 0.874049652382 0.877838884979 55502 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006139 ion binding Gene Ontology GO:0043167 1 962 0.881993177139 0.884538611993 84290 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043167 organic cyclic compound metabolic process Gene Ontology GO:1901360 1 971 0.884356200289 0.885630488762 8600 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:1901360 signaling Gene Ontology GO:0023052 1 984 0.887687122026 0.887687122026 10692 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0023052 --------------------