Genomic Region Gene Name Kiel Specific Accession_number Product COG COG category COG annotation GR_10 K04M3_RS17045 NO WP_017820101.1 LacI family transcriptional regulator COG1609 K helix_turn _helix lactose operon repressor GR_10 K04M3_RS17050 NO WP_005374733.1 sodium transporter COG0591 E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family GR_10 K04M3_RS17055 NO WP_086047201.1 polyketide cyclase COG5485 S SnoaL-like polyketide cyclase GR_10 K04M3_RS17060 NO WP_017820104.1 polyketide cyclase COG5485 S SnoaL-like polyketide cyclase GR_10 K04M3_RS17065 NO WP_054728860.1 hypothetical protein GR_11 K04M3_RS17800 NO WP_005375095.1 glycine C-acetyltransferase COG0156 H Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA GR_11 K04M3_RS17805 NO WP_005383983.1 L-threonine 3-dehydrogenase COG1063 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate GR_11 K04M3_RS17810 NO WP_005375099.1 SCPU domain-containing protein COG5430 S Spore Coat Protein U domain GR_11 K04M3_RS17815 NO WP_005375102.1 SCPU domain-containing protein COG5430 S Spore Coat GR_11 K04M3_RS17820 NO WP_054730629.1 protein CsuC COG3121 M chaperone GR_12 K04M3_RS19360 NO WP_086047309.1 ATP-dependent RNA helicase COG0513 JKL "DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation" GR_12 K04M3_RS19365 NO None hypothetical protein GR_12 K04M3_RS19370 NO WP_086013815.1 hypothetical protein GR_12 K04M3_RS19375 NO WP_005375697.1 acetate kinase COG0282 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction GR_12 K04M3_RS19380 NO WP_085569273.1 LysR family transcriptional regulator COG0583 K LysR substrate binding domain GR_12 K04M3_RS19385 NO WP_017635746.1 alpha/beta hydrolase COG1073 S of the alpha beta superfamily GR_12 K04M3_RS19390 NO WP_017635745.1 alpha/beta hydrolase COG1073 S X-Pro dipeptidyl-peptidase (S15 family) GR_12 K04M3_RS19395 NO WP_054574367.1 hypothetical protein GR_13 K04M3_RS20070 NO WP_086047352.1 branched-chain amino acid transporter COG4541 S Branched-chain amino acid transport protein (AzlD) GR_13 K04M3_RS20075 NO WP_086047353.1 branched-chain amino acid ABC transporter permease COG1296 E AzlC protein GR_13 K04M3_RS20080 NO WP_086047354.1 alanine racemase COG0787 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids GR_13 K04M3_RS20085 NO WP_086047355.1 methyl-accepting chemotaxis protein COG0840 NT methyl-accepting chemotaxis protein GR_13 K04M3_RS20090 YES WP_086047356.1 hypothetical protein COG5108 K DNA-dependent RNA polymerase GR_13 K04M3_RS20095 YES WP_029854548.1 hypothetical protein GR_13 K04M3_RS20100 YES WP_079741455.1 hypothetical protein GR_13 K04M3_RS20105 YES WP_042782765.1 hypothetical protein GR_13 K04M3_RS20110 YES WP_086047357.1 DNA primase "COG0305,COG0358" L Toprim-like GR_13 K04M3_RS20115 YES WP_086047358.1 hypothetical protein COG0749 L DNA polymerase family A GR_13 K04M3_RS20120 YES WP_031427788.1 hypothetical protein COG0749 L DNA polymerase family A GR_13 K04M3_RS20125 YES WP_086047359.1 hypothetical protein "4QAUT@10239,4QQ7X@28883,4QVIM@35237" S DNA ligase (ATP) activity GR_13 K04M3_RS20130 YES WP_086047360.1 hypothetical protein COG0258 L "5'-3' exonuclease, N-terminal resolvase-like domain" GR_13 K04M3_RS20135 YES WP_062866725.1 hypothetical protein COG0258 L "5'-3' exonuclease, N-terminal resolvase-like domain" GR_13 K04M3_RS20140 YES WP_086047361.1 hypothetical protein COG0258 L "5'-3' exonuclease, N-terminal resolvase-like domain" GR_13 K04M3_RS20145 YES WP_029854317.1 hypothetical protein COG1694 S PFAM MazG nucleotide pyrophosphohydrolase GR_13 K04M3_RS20150 YES WP_062866726.1 hypothetical protein "4QAZF@10239,4QNEM@10744,4QPH6@28883,4QUTY@35237" S Protein of unknwon function (DUF3310) GR_13 K04M3_RS20155 YES WP_062866727.1 hypothetical protein "4QAZF@10239,4QNEM@10744,4QPH6@28883,4QUTY@35237" S Protein of unknwon function (DUF3310) GR_13 K04M3_RS20160 YES WP_029854322.1 thymidylate synthase (FAD) 4QAUS@10239 S flavin adenine dinucleotide binding GR_13 K04M3_RS20165 YES WP_049877459.1 anaerobic ribonucleoside-triphosphate reductase COG1328 F ribonucleoside-triphosphate reductase GR_13 K04M3_RS20170 YES WP_029854327.1 hypothetical protein COG1328 F ribonucleoside-triphosphate reductase GR_13 K04M3_RS20175 YES WP_029854329.1 anaerobic ribonucleoside-triphosphate reductase activating protein "4QCT7@10239,4QIIN@10662,4QPFU@28883,4QVJT@35237" S "4 iron, 4 sulfur cluster binding" GR_13 K04M3_RS20180 YES WP_086047362.1 hypothetical protein COG1428 F Deoxynucleoside kinase GR_13 K04M3_RS20185 YES WP_062866731.1 hypothetical protein COG1428 F Deoxynucleoside kinase GR_13 K04M3_RS20190 YES WP_031810172.1 hypothetical protein "1R7CY@1224,28MSK@1,2ZB0X@2" S Bacteriophage head to tail connecting protein GR_13 K04M3_RS20195 YES WP_086047363.1 hypothetical protein "4QBAU@10239,4QNY1@10744,4QPEP@28883,4QW8E@35237" S viral capsid assembly GR_13 K04M3_RS20200 YES WP_086047364.1 hypothetical protein GR_13 K04M3_RS20205 YES WP_015727771.1 tail tubular protein A "1RH31@1224,2ATMD@1,2UBNT@28211,31J5V@2" S Tail tubular protein GR_13 K04M3_RS20210 YES WP_086047365.1 hypothetical protein GR_13 K04M3_RS20215 YES WP_086047366.1 hypothetical protein GR_13 K04M3_RS20220 YES WP_062866737.1 hypothetical protein GR_13 K04M3_RS20225 YES WP_086047367.1 hypothetical protein GR_13 K04M3_RS20230 YES WP_086047368.1 hypothetical protein GR_13 K04M3_RS20235 YES WP_086047369.1 hypothetical protein COG5301 G "cellulose 1,4-beta-cellobiosidase activity" GR_13 K04M3_RS20240 YES WP_079766853.1 hypothetical protein "4QB6G@10239,4QQS8@28883,4QVYX@35237" S carboxypeptidase activity GR_13 K04M3_RS20245 YES WP_015727779.1 hypothetical protein "4QB6G@10239,4QQS8@28883,4QVYX@35237" S carboxypeptidase activity GR_13 K04M3_RS20250 YES WP_015727781.1 HNH endonuclease "4QB6G@10239,4QQS8@28883,4QVYX@35237" S carboxypeptidase activity GR_13 K04M3_RS20255 YES WP_042782761.1 hypothetical protein "4QB6G@10239,4QQS8@28883,4QVYX@35237" S carboxypeptidase activity GR_13 K04M3_RS20260 YES WP_079766858.1 DNA maturase B COG5410 K chromosome segregation GR_13 K04M3_RS20265 YES WP_086047370.1 hypothetical protein COG5410 K chromosome segregation GR_13 K04M3_RS20270 YES WP_086047371.1 hypothetical protein COG5410 K chromosome segregation GR_13 K04M3_RS20275 YES WP_086047372.1 hypothetical protein COG5410 K chromosome segregation GR_13 K04M3_RS20280 YES WP_062866745.1 hypothetical protein COG5410 K chromosome segregation GR_13 K04M3_RS20285 YES WP_086047373.1 hypothetical protein GR_13 K04M3_RS20290 YES WP_086047374.1 hypothetical protein COG4734 S Antirestriction protein (ArdA) GR_13 K04M3_RS20295 YES WP_086047375.1 hypothetical protein COG4734 S Antirestriction protein (ArdA) GR_13 K04M3_RS20300 YES WP_086047376.1 hypothetical protein arCOG09463 L DNA-sulfur modification-associated GR_13 K04M3_RS20305 YES WP_086047377.1 hypothetical protein arCOG09463 L DNA-sulfur modification-associated GR_13 K04M3_RS20310 YES WP_062866751.1 hypothetical protein arCOG09463 L DNA-sulfur modification-associated GR_13 K04M3_RS20315 YES WP_062866752.1 integrase COG0582 L Phage integrase family GR_13 K04M3_RS20320 YES WP_062866753.1 hypothetical protein COG0582 L Phage integrase family GR_13 K04M3_RS20335 NO WP_054576737.1 alpha-amylase COG0366 G Glycosyl hydrolase family 70 GR_14 K04M3_RS20675 NO WP_025767766.1 histidine kinase COG0642 T COG0642 Signal transduction histidine kinase GR_14 K04M3_RS20680 NO WP_005376251.1 DNA-binding response regulator COG0745 K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain GR_14 K04M3_RS20685 NO WP_053303637.1 hypothetical protein "1QJBY@1224,1THAZ@1236,1XSXM@135623,2BTFF@1,32NMR@2" S Protein of unknown function (DUF2861) GR_14 K04M3_RS20690 NO WP_005388052.1 conjugal transfer protein TraF "1N1QM@1224,1RR0J@1236,1XSR0@135623,28IW1@1,2Z8UB@2" S "F plasmid transfer operon, TraF, protein" GR_14 K04M3_RS20695 NO WP_005376257.1 YoaH family protein COG3140 S Belongs to the UPF0181 family GR_14 K04M3_RS20700 NO WP_017634770.1 universal stress protein COG0589 T Universal stress protein family GR_14 K04M3_RS20705 NO WP_005376260.1 hypothetical protein GR_14 K04M3_RS20710 NO WP_025998628.1 LysR family transcriptional regulator COG0583 K "Bacterial regulatory helix-turn-helix protein, lysR family" GR_14 K04M3_RS20715 NO None hypothetical protein GR_14 K04M3_RS20720 NO WP_017634767.1 hypothetical protein COG0583 K "Bacterial regulatory helix-turn-helix protein, lysR family" GR_14 K04M3_RS20725 NO WP_086047390.1 hypothetical protein COG0583 K "Bacterial regulatory helix-turn-helix protein, lysR family" GR_14 K04M3_RS20730 YES WP_086047391.1 hypothetical protein COG0583 K "Bacterial regulatory helix-turn-helix protein, lysR family" GR_14 K04M3_RS20735 YES WP_086071126.1 hypothetical protein COG0583 K "Bacterial regulatory helix-turn-helix protein, lysR family" GR_14 K04M3_RS20740 YES WP_086047393.1 hypothetical protein GR_14 K04M3_RS20745 YES WP_086047394.1 hypothetical protein COG2842 S Bacterial TniB protein GR_14b K04M3_RS20760 YES WP_086047397.1 hypothetical protein COG2801 L Transposase and inactivated derivatives GR_14b K04M3_RS20765 YES WP_086047398.1 MBL fold metallo-hydrolase COG2333 S Beta-lactamase superfamily domain GR_14b K04M3_RS20770 YES WP_086047399.1 serine protease COG0265 O "Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain" GR_14b K04M3_RS20775 YES WP_086047400.1 hypothetical protein COG0265 O "Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain" GR_14b K04M3_RS20780 YES None DNA repair protein COG1196 L nuclear chromosome segregation GR_14b K04M3_RS20785 YES WP_086047401.1 hypothetical protein GR_14b K04M3_RS20790 YES WP_042765525.1 hypothetical protein GR_14b K04M3_RS20795 YES WP_086047402.1 hypothetical protein GR_14b K04M3_RS20800 YES WP_086047403.1 hypothetical protein GR_14b K04M3_RS20805 YES WP_080369130.1 hypothetical protein GR_14b K04M3_RS20810 YES WP_017636215.1 toxin COG4128 S Zonular occludens toxin (Zot) GR_15 K04M3_RS20855 NO WP_086048341.1 hypothetical protein "1N2J0@1224,1SBVC@1236,1XZ5A@135623,2DN9C@1,32W8M@2" S Phage related protein GR_15 K04M3_RS20860 YES WP_025572405.1 hypothetical protein GR_15 K04M3_RS20865 YES WP_045091503.1 hypothetical protein GR_15 K04M3_RS20870 NO WP_045607620.1 assembly protein COG4128 S Zonular occludens toxin (Zot) GR_15 K04M3_RS20875 NO WP_017822026.1 VSK receptor "1NM75@1224,1SUNZ@1236,1Y1UP@135623,2CHQ6@1,33N6R@2" S Protein of unknown function (DUF2523) GR_15 K04M3_RS20880 YES WP_045091826.1 methyl-accepting chemotaxis protein GR_15 K04M3_RS20885 YES WP_070363891.1 phage coat protein GR_15 K04M3_RS20890 YES WP_015975174.1 hypothetical protein "4QAV9@10239,4QP4Q@10860,4QUKQ@29258" S integral to membrane GR_15 K04M3_RS20895 NO WP_086486521.1 hypothetical protein "1QK9E@1224,1TICW@1236,1XYW5@135623,2AWN0@1,31NIS@2" S Protein of unknown function (DUF1293) GR_15 K04M3_RS20900 NO WP_080480184.1 phage replication protein COG2946 L Replication initiation factor GR_15 K04M3_RS20905 YES WP_029826510.1 hypothetical protein GR_15 K04M3_RS20910 NO WP_086048342.1 hypothetical protein GR_15 K04M3_RS20915 YES WP_086486522.1 hypothetical protein "1N2J0@1224,1SBVC@1236,1XY4C@135623,2DN9C@1,32W8M@2" S Phage related protein GR_15 K04M3_RS20920 NO WP_042765525.1 hypothetical protein GR_15 K04M3_RS20925 YES WP_086047402.1 hypothetical protein GR_15 K04M3_RS20930 YES WP_086047403.1 hypothetical protein GR_15 K04M3_RS20935 NO WP_045607620.1 assembly protein COG4128 S Zonular occludens toxin (Zot) GR_15 K04M3_RS20940 NO WP_017822026.1 VSK receptor "1NM75@1224,1SUNZ@1236,1Y1UP@135623,2CHQ6@1,33N6R@2" S Protein of unknown function (DUF2523) GR_15 K04M3_RS20945 NO WP_045091826.1 methyl-accepting chemotaxis protein GR_15 K04M3_RS20950 YES WP_070363891.1 phage coat protein GR_15 K04M3_RS20955 YES WP_015975174.1 hypothetical protein "4QAV9@10239,4QP4Q@10860,4QUKQ@29258" S integral to membrane GR_15 K04M3_RS20960 YES WP_086486521.1 hypothetical protein "1QK9E@1224,1TICW@1236,1XYW5@135623,2AWN0@1,31NIS@2" S Protein of unknown function (DUF1293) GR_15 K04M3_RS20965 NO WP_080480184.1 phage replication protein COG2946 L Replication initiation factor GR_15 K04M3_RS20970 NO WP_029826510.1 hypothetical protein GR_15 K04M3_RS20975 YES WP_045346885.1 hypothetical protein "1N2J0@1224,1SBVC@1236,1XY4C@135623,2DN9C@1,32W8M@2" S Phage related protein GR_15 K04M3_RS20980 NO None stress response translation initiation inhibitor YciH GR_15 K04M3_RS20985 NO None phage tail protein "1QJSF@1224,1THTS@1236,1XXI7@135623,2AW5Q@1,31N0Q@2" S Protein of unknown function (DUF3319) GR_15 K04M3_RS20990 NO None D-alanine--D-alanine ligase A GR_15 K04M3_RS20995 NO None cytochrome C biogenesis protein CcdA GR_15 K04M3_RS21000 NO None protein acetyltransferase GR_15 K04M3_RS21005 YES WP_017634152.1 LysR family transcriptional regulator COG0583 K Transcriptional regulator GR_15 K04M3_RS21010 NO None TonB-dependent receptor GR_15 K04M3_RS21015 YES WP_086486523.1 hypothetical protein "COG1629,COG4771" P "COG1629 Outer membrane receptor proteins, mostly Fe transport" GR_15 K04M3_RS21020 YES WP_086486524.1 hypothetical protein "COG1629,COG4771" P "COG1629 Outer membrane receptor proteins, mostly Fe transport" GR_15 K04M3_RS21025 YES WP_080369130.1 hypothetical protein "COG1629,COG4771" P "COG1629 Outer membrane receptor proteins, mostly Fe transport" GR_15 K04M3_RS21030 NO None toxin GR_15 K04M3_RS21035 YES None DUF2523 domain-containing protein "COG1629,COG4771" P "COG1629 Outer membrane receptor proteins, mostly Fe transport" GR_15 K04M3_RS21040 NO None hypothetical protein GR_15 K04M3_RS21045 NO WP_011105866.1 hypothetical protein GR_15 K04M3_RS21050 YES None hypothetical protein "COG1629,COG4771" P "COG1629 Outer membrane receptor proteins, mostly Fe transport" GR_15 K04M3_RS21055 YES WP_005477619.1 hypothetical protein "COG1629,COG4771" P "COG1629 Outer membrane receptor proteins, mostly Fe transport" GR_15 K04M3_RS21060 YES WP_053303056.1 hypothetical protein "1QK9E@1224,1TICW@1236,1XYW5@135623,2AWN0@1,31NIS@2" S Protein of unknown function (DUF1293) GR_15 K04M3_RS21065 YES WP_086047405.1 phage replication protein COG2946 L Replication initiation factor GR_15 K04M3_RS21070 YES WP_005477640.1 hypothetical protein GR_15 K04M3_RS21075 YES WP_086486525.1 hypothetical protein "1N2J0@1224,1SBVC@1236,1XZ5A@135623,2DN9C@1,32W8M@2" S Phage related protein GR_15 K04M3_RS21080 YES WP_086486526.1 regulator GR_15 K04M3_RS21085 YES WP_045091503.1 hypothetical protein GR_15 K04M3_RS21090 YES WP_045607620.1 assembly protein COG4128 S Zonular occludens toxin (Zot) GR_15 K04M3_RS21095 YES WP_017822026.1 VSK receptor "1NM75@1224,1SUNZ@1236,1Y1UP@135623,2CHQ6@1,33N6R@2" S Protein of unknown function (DUF2523) GR_15 K04M3_RS21100 YES WP_045091826.1 methyl-accepting chemotaxis protein GR_15 K04M3_RS21105 YES WP_070363891.1 phage coat protein GR_15 K04M3_RS21110 YES WP_015975174.1 hypothetical protein "4QAV9@10239,4QP4Q@10860,4QUKQ@29258" S integral to membrane GR_15 K04M3_RS21115 NO WP_086486521.1 hypothetical protein "1QK9E@1224,1TICW@1236,1XYW5@135623,2AWN0@1,31NIS@2" S Protein of unknown function (DUF1293) GR_15 K04M3_RS21120 YES WP_080480184.1 phage replication protein COG2946 L Replication initiation factor GR_15 K04M3_RS21125 YES WP_029826510.1 hypothetical protein GR_15 K04M3_RS21130 NO WP_086048342.1 hypothetical protein GR_16 K04M3_RS22510 NO WP_005373333.1 NAD(P)-dependent oxidoreductase COG4221 S Belongs to the short-chain dehydrogenases reductases (SDR) family GR_16 K04M3_RS22515 NO WP_005373334.1 LysR family transcriptional regulator COG0583 K Transcriptional regulator GR_16 K04M3_RS22520 NO WP_017820362.1 AraC family transcriptional regulator COG2207 K COG2207 AraC-type DNA-binding domain-containing proteins GR_16 K04M3_RS22525 NO WP_086047482.1 MFS transporter "COG0477,COG2814" EGP Major facilitator Superfamily GR_16 K04M3_RS22530 NO WP_054577796.1 hypothetical protein GR_16 K04M3_RS22535 NO WP_031778823.1 hypothetical protein GR_16 K04M3_RS22540 NO WP_005373345.1 hypothetical protein GR_16 K04M3_RS22545 NO WP_086047483.1 hypothetical protein "COG1070,COG3179" G lysozyme GR_16 K04M3_RS22550 NO WP_086047484.1 hypothetical protein COG1196 D Domain of unknown function (DUF4150) GR_16 K04M3_RS22555 NO WP_086013796.1 type VI secretion protein COG3455 N VI Secretion GR_16 K04M3_RS22560 NO WP_086047485.1 type VI secretion system-associated protein COG3522 S protein conserved in bacteria GR_16 K04M3_RS22565 NO WP_005386118.1 type VI secretion lipoprotein COG3521 S "Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113" GR_17 K04M3_RS22685 NO WP_086047619.1 hypothetical protein COG2373 S Large extracellular alpha-helical protein GR_18 K04M3_RS22695 NO WP_005373432.1 antibiotic acetyltransferase COG0110 S Bacterial transferase hexapeptide (six repeats) GR_18 K04M3_RS22700 NO WP_005373435.1 class C beta-lactamase COG1680 V Beta-lactamase GR_18 K04M3_RS22705 NO WP_086047491.1 GntR family transcriptional regulator COG1167 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs GR_18 K04M3_RS22710 NO WP_080773710.1 hypothetical protein GR_18 K04M3_RS22715 NO WP_086047492.1 hypothetical protein "COG2304,COG2931,COG3637" Q Putative Ig domain GR_19 K04M3_RS22715 NO WP_086047492.1 hypothetical protein "COG2304,COG2931,COG3637" Q Putative Ig domain GR_19 K04M3_RS22720 NO WP_005373442.1 microcystin dependent protein COG4675 S Phage Tail Collar Domain GR_19 K04M3_RS22725 NO WP_086047493.1 hypothetical protein COG0223 J "Formyl transferase, C-terminal domain" GR_19 K04M3_RS22730 NO WP_053307255.1 hypothetical protein COG5285 Q phytanoyl-CoA dioxygenase GR_19 K04M3_RS22735 NO WP_025767914.1 ATPase "COG0457,COG3899" K AAA ATPase domain GR_19 K04M3_RS22740 NO WP_005373450.1 hypothetical protein "1N92S@1224,1SZR7@1236,2EB53@1,3355S@2" S Domain of unknown function (DUF1842) GR_19 K04M3_RS22745 NO WP_086047494.1 FAD-binding protein COG0277 C FAD linked oxidase domain protein GR_19 K04M3_RS22750 NO WP_005373454.1 hypothetical protein COG0277 C FAD linked oxidase domain protein GR_19 K04M3_RS22755 NO WP_086047495.1 choloylglycine hydrolase COG3049 M "Linear amide C-N hydrolases, choloylglycine hydrolase family" GR_1 K10K4_RS00925 NO WP_086046446.1 diacylglycerol kinase COG0818 M Recycling of diacylglycerol produced during the turnover of membrane phospholipid GR_1 K10K4_RS00930 NO WP_086046447.1 3-deoxy-D-manno-octulosonic acid kinase COG3642 H Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position GR_1 K10K4_RS00935 NO WP_086046448.1 "dTDP-glucose 4,6-dehydratase" COG1088 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily GR_1 K10K4_RS00940 NO WP_086046449.1 glucose-1-phosphate thymidylyltransferase COG1209 H "Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis" GR_1 K10K4_RS00945 NO WP_048625666.1 "dTDP-6-deoxy-3,4-keto-hexulose isomerase" COG1898 M "WxcM-like, C-terminal" GR_1 K10K4_RS00950 NO WP_047009430.1 N-acetyltransferase COG0110 S COG0110 Acetyltransferase (isoleucine patch superfamily) GR_1 K10K4_RS00955 NO WP_086046450.1 aminotransferase COG0399 E Belongs to the DegT DnrJ EryC1 family GR_1 K10K4_RS00960 NO WP_086046451.1 glycosyl transferase family 2 COG1215 M Glycosyl transferase family 2 GR_1 K10K4_RS00965 NO WP_086046452.1 hypothetical protein GR_1 K10K4_RS00970 NO WP_047009434.1 acylneuraminate cytidylyltransferase COG1083 M Cytidylyltransferase GR_1 K10K4_RS00975 NO WP_047009435.1 HAD family hydrolase COG0546 S Hydrolase GR_1 K10K4_RS00980 NO WP_047009436.1 pyruvate carboxyltransferase COG0119 E HMGL-like GR_1 K10K4_RS00985 NO WP_086046453.1 3-deoxy-D-manno-octulosonic acid transferase COG1519 M 3-deoxy-D-manno-octulosonic-acid transferase GR_1 K10K4_RS00990 NO WP_005379458.1 lipopolysaccharide heptosyltransferase II COG0859 M ADP-heptose--LPS heptosyltransferase II GR_1 K10K4_RS00995 NO WP_086046454.1 glycosyltransferase COG3306 M Glycosyltransferase family 25 (LPS biosynthesis protein) GR_1 K10K4_RS01000 NO WP_086046455.1 lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase COG1560 M Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)-lipid A GR_1 K10K4_RS01005 YES WP_086046456.1 hypothetical protein COG3306 M Glycosyltransferase family 25 (LPS biosynthesis protein) GR_1 K10K4_RS01010 YES WP_086046457.1 hypothetical protein COG3307 M COG3307 Lipid A core - O-antigen ligase and related enzymes GR_1 K10K4_RS01015 NO WP_086046458.1 ADP-glyceromanno-heptose 6-epimerase COG0451 GM Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose GR_1 K10K4_RS01020 NO WP_086046459.1 hypothetical protein COG4775 M Exopolysaccharide biosynthesis protein YbjH GR_1 K10K4_RS01025 YES WP_086046460.1 YjbG polysaccharide synthesis-related protein "1NG4X@1224,1RZ19@1236,1XYIU@135623,29T7B@1,30EE4@2" S Capsule biosynthesis GfcC GR_1 K10K4_RS01030 YES WP_025503634.1 YjbF family lipoprotein "1N1VT@1224,1RMP6@1236,1XXFZ@135623,28M8B@1,2ZAMG@2" S "Group 4 capsule polysaccharide lipoprotein gfcB, YjbF" GR_1 K10K4_RS01035 YES WP_025503633.1 hypothetical protein "1N1VT@1224,1RMP6@1236,1XXFZ@135623,28M8B@1,2ZAMG@2" S "Group 4 capsule polysaccharide lipoprotein gfcB, YjbF" GR_1 K10K4_RS01040 NO WP_086047115.1 wbfE protein COG3637 M Outer membrane protein beta-barrel domain GR_1 K10K4_RS01045 NO WP_086046461.1 OtnA protein COG1596 M Periplasmic protein involved in polysaccharide export GR_1 K10K4_RS01050 YES WP_086046462.1 LPS O-antigen length regulator COG3765 M Chain length determinant protein GR_1 K10K4_RS01055 YES WP_086046463.1 hypothetical protein COG0151 F phosphoribosylamine-glycine ligase activity GR_1 K10K4_RS01060 YES WP_086046464.1 hypothetical protein COG0686 E "Alanine dehydrogenase/PNT, C-terminal domain" GR_1 K10K4_RS01065 YES WP_086046465.1 polysaccharide biosynthesis protein COG2244 S Polysaccharide biosynthesis protein GR_1 K10K4_RS01070 YES WP_086047116.1 hypothetical protein COG0438 M glycosyl transferase group 1 GR_1 K10K4_RS01075 YES WP_086046466.1 hypothetical protein "1NI7M@1224,1SI5T@1236,2EN1N@1,33FPU@2" S EpsG family GR_1 K10K4_RS01080 YES WP_086046467.1 glycosyl transferase COG0438 M Glycosyl transferase 4-like GR_1 K10K4_RS01085 YES WP_086046468.1 hypothetical protein COG0438 M Glycosyl transferases group 1 GR_1 K10K4_RS01090 NO WP_086046469.1 exopolysaccharide biosynthesis protein COG2148 M COG2148 Sugar transferases involved in lipopolysaccharide synthesis GR_1 K10K4_RS01095 NO WP_086046470.1 MBL fold hydrolase COG1236 J exonuclease of the beta-lactamase fold involved in RNA processing GR_1 K10K4_RS01100 NO WP_086046471.1 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase COG0472 M "Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55)" GR_1 K10K4_RS01105 YES WP_086046472.1 polysaccharide biosynthesis protein COG2244 S Polysaccharide biosynthesis protein GR_1 K10K4_RS01110 YES WP_086046473.1 hypothetical protein COG0438 M Glycosyl transferases group 1 GR_1 K10K4_RS01115 YES WP_086046474.1 hypothetical protein arCOG09256 GR_1 K10K4_RS01120 YES WP_086046475.1 hypothetical protein arCOG09256 GR_1 K10K4_RS01125 YES WP_086046476.1 hypothetical protein COG1216 S Glycosyl transferase GR_1 K10K4_RS01130 YES WP_086046477.1 glycosyl transferase family 2 COG0463 M COG0463 Glycosyltransferases involved in cell wall biogenesis GR_2 K10K4_RS03030 NO WP_005381685.1 GMP synthase (glutamine-hydrolyzing) "COG0518,COG0519" F Catalyzes the synthesis of GMP from XMP GR_2 K10K4_RS03035 YES WP_086046548.1 integrase COG0582 L Belongs to the 'phage' integrase family GR_2 K10K4_RS03040 YES WP_020840144.1 hypothetical protein COG0457 S Domain of unknown function (DUF4365) GR_2 K10K4_RS03045 YES WP_086046549.1 transcriptional regulator GR_2 K10K4_RS03050 YES WP_025505671.1 AlpA family transcriptional regulator COG3311 K transcriptional regulator GR_2 K10K4_RS03055 YES WP_021822292.1 plasmid encoded RepA family protein "1RAPA@1224,1SFYE@1236,28MWI@1,2ZB3T@2" S Plasmid encoded RepA protein GR_2 K10K4_RS03060 YES WP_025505673.1 conjugal transfer protein TrbJ COG5314 U Conjugal transfer GR_2 K10K4_RS03065 YES WP_050498103.1 entry exclusion lipoprotein TrbK GR_2 K10K4_RS03070 YES WP_086047121.1 P-type conjugative transfer protein TrbL COG3846 U Conjugal transfer protein GR_2 K10K4_RS03075 YES WP_086046550.1 reverse transcriptase COG3344 L Reverse transcriptase (RNA-dependent DNA polymerase) GR_2 K10K4_RS03080 YES WP_069486098.1 ATP-binding protein COG3593 L DNA synthesis involved in DNA repair GR_2 K10K4_RS03085 YES WP_062853952.1 hypothetical protein GR_2 K10K4_RS03090 YES WP_062853951.1 hypothetical protein COG3600 K Phage-associated protein GR_2 K10K4_RS03095 YES WP_062853950.1 hypothetical protein GR_2 K10K4_RS03100 NO WP_054730033.1 sodium:proton exchanger COG1757 C C4-dicarboxylate anaerobic carrier GR_3 K10K4_RS06400 NO WP_086046658.1 exodeoxyribonuclease I COG2925 L COG2925 Exonuclease I GR_3 K10K4_RS06405 NO WP_086046659.1 integrase COG0582 L Belongs to the 'phage' integrase family GR_3 K10K4_RS06410 YES WP_086046660.1 hypothetical protein COG0582 L Belongs to the 'phage' integrase family GR_3 K10K4_RS06415 YES WP_086046661.1 hypothetical protein GR_3 K10K4_RS06420 YES WP_086046662.1 hypothetical protein GR_3 K10K4_RS06425 YES WP_086046663.1 hypothetical protein "1N4EI@1224,2F8UM@1,3416M@2" Q "Taurine catabolism dioxygenase TauD, TfdA family" GR_3 K10K4_RS06430 YES WP_086046664.1 hypothetical protein GR_3 K10K4_RS06435 YES WP_086046665.1 hypothetical protein GR_3 K10K4_RS06440 YES WP_086046666.1 hypothetical protein GR_3 K10K4_RS06445 NO WP_086046667.1 hypothetical protein GR_3 K10K4_RS06450 NO WP_025766807.1 hypothetical protein GR_3 K10K4_RS06455 YES WP_086046668.1 hypothetical protein COG0272 L BRCA1 C Terminus (BRCT) domain GR_4 K10K4_RS07070 YES WP_086047132.1 transcriptional regulator COG1961 L Recombinase GR_4 K10K4_RS07075 YES WP_086046708.1 hypothetical protein COG1961 L Recombinase GR_4 K10K4_RS07080 YES WP_086046709.1 hypothetical protein COG1961 L Recombinase GR_4 K10K4_RS07085 YES WP_086046710.1 hypothetical protein COG1961 L Recombinase GR_4 K10K4_RS07090 YES WP_086046711.1 hypothetical protein COG1961 L Recombinase GR_4 K10K4_RS07095 YES WP_086046712.1 resolvase COG1961 L "COG1961 Site-specific recombinases, DNA invertase Pin homologs" GR_4 K10K4_RS07100 YES WP_086046713.1 hypothetical protein "4QB2Z@10239,4QHWJ@10662,4QPYN@28883,4QWQN@35237" S "gp45 sliding clamp, C terminal" GR_4 K10K4_RS07105 YES WP_086046714.1 hypothetical protein "4QB2Z@10239,4QHWJ@10662,4QPYN@28883,4QWQN@35237" S "gp45 sliding clamp, C terminal" GR_4 K10K4_RS07110 YES WP_086046715.1 hypothetical protein "4QB2Z@10239,4QHWJ@10662,4QPYN@28883,4QWQN@35237" S "gp45 sliding clamp, C terminal" GR_4 K10K4_RS07115 YES WP_086046716.1 hypothetical protein GR_4 K10K4_RS07120 YES WP_086046717.1 hypothetical protein GR_4 K10K4_RS07125 YES WP_016791685.1 hypothetical protein GR_4 K10K4_RS07130 NO WP_086046718.1 hypothetical protein GR_4 K10K4_RS07135 YES WP_086046719.1 hypothetical protein GR_4 K10K4_RS07140 YES WP_086055064.1 hypothetical protein GR_4 K10K4_RS07145 YES WP_086046721.1 hypothetical protein GR_4 K10K4_RS07150 YES WP_078580698.1 hypothetical protein GR_4 K10K4_RS07155 YES WP_086046722.1 hypothetical protein GR_4 K10K4_RS07160 YES WP_086046723.1 hypothetical protein GR_4 K10K4_RS07165 YES WP_086046724.1 hypothetical protein GR_4 K10K4_RS07170 YES WP_086046725.1 hypothetical protein GR_4 K10K4_RS07175 YES WP_086047133.1 hypothetical protein GR_4 K10K4_RS07180 YES WP_086046726.1 hypothetical protein GR_4 K10K4_RS07185 YES WP_086046727.1 hypothetical protein GR_5 K10K4_RS08025 NO WP_086048342.1 hypothetical protein "1N2J0@1224,1SBVC@1236,1XY4C@135623,2DN9C@1,32W8M@2" S Phage related protein GR_5 K10K4_RS08030 YES WP_029826510.1 hypothetical protein GR_5 K10K4_RS08035 NO WP_080480184.1 phage replication protein COG2946 L Replication initiation factor GR_5 K10K4_RS08040 NO WP_017822035.1 hypothetical protein "1QK9E@1224,1TICW@1236,1XYW5@135623,2AWN0@1,31NIS@2" S Protein of unknown function (DUF1293) GR_5 K10K4_RS08045 YES WP_015975174.1 hypothetical protein "4QAV9@10239,4QP4Q@10860,4QUKQ@29258" S integral to membrane GR_5 K10K4_RS08050 YES WP_070363891.1 phage coat protein "4QAV9@10239,4QP4Q@10860,4QUKQ@29258" S integral to membrane GR_5 K10K4_RS08055 YES WP_045091826.1 methyl-accepting chemotaxis protein GR_5 K10K4_RS08060 NO WP_017822026.1 VSK receptor "1NM75@1224,1SUNZ@1236,1Y1UP@135623,2CHQ6@1,33N6R@2" S Protein of unknown function (DUF2523) GR_5 K10K4_RS08065 NO WP_045607620.1 assembly protein COG4128 S Zonular occludens toxin (Zot) GR_5 K10K4_RS08070 YES WP_045091503.1 hypothetical protein COG4128 S Zonular occludens toxin (Zot) GR_5 K10K4_RS08075 YES WP_025572405.1 hypothetical protein GR_5 K10K4_RS08080 NO WP_054730190.1 hypothetical protein GR_6 K10K4_RS09170 NO WP_086046821.1 DUF3265 domain-containing protein GR_6 K10K4_RS09175 YES WP_086047141.1 hypothetical protein COG1403 V HNH nucleases GR_6 K10K4_RS09180 YES WP_045397058.1 hypothetical protein COG1403 V HNH nucleases GR_6 K10K4_RS09185 NO WP_086046822.1 hypothetical protein GR_6 K10K4_RS09190 NO WP_086046823.1 DUF3265 domain-containing protein GR_6 K10K4_RS09195 YES WP_054730841.1 DUF2569 domain-containing protein COG0697 EG Protein of unknown function (DUF2569) GR_6 K10K4_RS09200 YES WP_086046824.1 hypothetical protein COG0697 EG Protein of unknown function (DUF2569) GR_6 K10K4_RS09205 YES WP_054730801.1 hypothetical protein COG0697 EG Protein of unknown function (DUF2569) GR_6 K10K4_RS09210 YES WP_054730804.1 hypothetical protein COG4127 S Restriction endonuclease GR_6 K10K4_RS09215 NO None DUF3265 domain-containing protein GR_6 K10K4_RS09220 NO WP_086046825.1 DUF3265 domain-containing protein GR_6 K10K4_RS09225 YES WP_086046826.1 hypothetical protein COG4127 S Restriction endonuclease GR_6 K10K4_RS09230 NO WP_086047142.1 DUF3265 domain-containing protein GR_6 K10K4_RS09235 YES WP_050550131.1 IS30 family transposase COG2826 L "other refs with uncharged polar side chains (S Ser or T Thr), and there are a few more such examples along the aa-chain (ex R Arg changed with H His)" GR_6 K10K4_RS09240 YES WP_054730813.1 hypothetical protein COG2826 L "other refs with uncharged polar side chains (S Ser or T Thr), and there are a few more such examples along the aa-chain (ex R Arg changed with H His)" GR_6 K10K4_RS09245 NO WP_079765356.1 DUF3265 domain-containing protein GR_6 K10K4_RS09250 YES WP_086046827.1 integrase COG0582 L Belongs to the 'phage' integrase family GR_6 K10K4_RS09255 YES WP_086046828.1 hypothetical protein COG0582 L Belongs to the 'phage' integrase family GR_6 K10K4_RS09260 NO WP_086047143.1 hypothetical protein COG0582 L Belongs to the 'phage' integrase family GR_6 K10K4_RS09265 YES WP_086046829.1 integrase COG4974 L Phage integrase family GR_6 K10K4_RS09270 NO None IS91 family transposase GR_6 K10K4_RS09275 YES WP_086046830.1 hypothetical protein COG5001 T Diguanylate cyclase GR_6 K10K4_RS09280 YES None IS3 family transposase COG2801 L Transposase GR_6 K10K4_RS09285 NO None IS110 family transposase GR_6 K10K4_RS09290 YES WP_086047144.1 transporter COG2985 S Predicted Permease Membrane Region GR_6 K10K4_RS09295 YES WP_086046831.1 glutamate decarboxylase COG0076 E Belongs to the group II decarboxylase family GR_6 K10K4_RS09300 NO WP_086046832.1 hypothetical protein GR_6 K10K4_RS09305 YES WP_086046833.1 magnesium and cobalt transport protein CorA COG0598 P Mediates influx of magnesium ions GR_6 K10K4_RS09310 YES WP_086047145.1 hypothetical protein COG4775 M "Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane" GR_6 K10K4_RS09315 YES WP_086046834.1 calcium:proton antiporter COG0387 P Sodium calcium exchanger membrane GR_6 K10K4_RS09320 YES WP_086046835.1 hypothetical protein COG0387 P Sodium calcium exchanger membrane GR_6 K10K4_RS09325 YES WP_086046836.1 hypothetical protein COG1226 P Ion channel GR_6 K10K4_RS09330 YES WP_086046837.1 hypothetical protein COG1538 MU CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) GR_6 K10K4_RS09335 YES WP_086046838.1 hypothetical protein COG1289 S Resistance protein GR_6 K10K4_RS09340 YES WP_086046839.1 multidrug transporter subunit MdtN COG1566 V HlyD membrane-fusion protein of T1SS GR_6 K10K4_RS09345 YES WP_086046840.1 hypothetical protein "1N7UH@1224,1SG5V@1236,2DNXZ@1,32ZQR@2" S Uncharacterised protein family GR_6 K10K4_RS09350 YES WP_086047146.1 linear amide C-N hydrolase COG3049 M Hydrolase GR_6 K10K4_RS09355 YES WP_086046841.1 choloylglycine hydrolase COG3049 M PFAM Choloylglycine hydrolase GR_6 K10K4_RS09360 YES WP_086046842.1 aspartate-alanine antiporter COG2985 U Predicted Permease Membrane Region GR_6 K10K4_RS09365 YES WP_086046843.1 Na+/H+ antiporter COG0025 P Sodium/hydrogen exchanger family GR_6 K10K4_RS09370 YES WP_086046844.1 choloylglycine hydrolase COG3049 M PFAM Choloylglycine hydrolase GR_6 K10K4_RS09375 NO None transposase GR_6 K10K4_RS09380 NO WP_086046845.1 hypothetical protein GR_6 K10K4_RS09385 NO None IS66 family transposase GR_6 K10K4_RS09390 YES WP_086046846.1 dimethylsulfoxide reductase COG3302 S DMSO reductase anchor subunit (DmsC) GR_6 K10K4_RS09395 YES WP_086046847.1 "dimethylsulfoxide reductase, chain B" COG0437 C 4Fe-4S dicluster domain GR_6 K10K4_RS09400 YES WP_086046848.1 dimethyl sulfoxide reductase subunit A COG0243 C Molybdopterin oxidoreductase Fe4S4 domain GR_6 K10K4_RS09405 YES WP_086046849.1 dimethylsulfoxide reductase COG3381 S Nitrate reductase delta subunit GR_6 K10K4_RS09410 YES WP_086046850.1 ferredoxin-type protein NapF COG1145 C 4Fe-4S binding domain GR_6 K10K4_RS09415 YES WP_086046851.1 hybrid sensor histidine kinase/response regulator COG0642 T His Kinase A (phospho-acceptor) domain GR_6 K10K4_RS09420 YES WP_086046852.1 hypothetical protein COG0642 T His Kinase A (phospho-acceptor) domain GR_6 K10K4_RS09425 NO WP_045545245.1 transcriptional regulator COG1396 K Helix-turn-helix XRE-family like proteins GR_6 K10K4_RS09430 NO WP_086046853.1 hypothetical protein GR_6 K10K4_RS09435 NO WP_045545244.1 transcriptional regulator COG3311 K Transcriptional regulator GR_6 K10K4_RS09440 YES WP_086046854.1 chromosome segregation ATPase COG3311 K Transcriptional regulator GR_6 K10K4_RS09445 YES WP_086046855.1 relaxase COG3843 U Relaxase/Mobilisation nuclease domain GR_6 K10K4_RS09450 NO None hypothetical protein GR_6 K10K4_RS09455 NO None transcriptional regulator GR_6 K10K4_RS09460 YES None hypothetical protein COG0477 EGP Major facilitator Superfamily GR_6 K10K4_RS09465 YES WP_086046856.1 hypothetical protein COG2207 K "PFAM helix-turn-helix- domain containing protein, AraC type" GR_6 K10K4_RS09470 NO None hypothetical protein GR_6 K10K4_RS09475 YES WP_086046857.1 C4-dicarboxylate ABC transporter COG1275 P Voltage-dependent anion channel GR_6 K10K4_RS09480 YES WP_086046858.1 alkylhydroperoxidase COG0599 S Carboxymuconolactone decarboxylase family GR_6 K10K4_RS09485 YES WP_086046859.1 LuxR family transcriptional regulator COG2259 S DoxX GR_6 K10K4_RS09490 YES WP_086046860.1 hypothetical protein COG3477 S response to acidic pH GR_6 K10K4_RS09495 YES WP_086046861.1 hypothetical protein "COG0784,COG2200" T Putative diguanylate phosphodiesterase GR_6 K10K4_RS09500 YES WP_086046862.1 hypothetical protein COG2197 K "helix_turn_helix, Lux Regulon" GR_6 K10K4_RS09505 YES WP_086046863.1 hypothetical protein COG3121 M "Pili and flagellar-assembly chaperone, PapD N-terminal domain" GR_6 K10K4_RS09510 YES WP_086046864.1 hypothetical protein "1R4XB@1224,1RNFY@1236,28J32@1,2Z8ZC@2" S "Part of the ecpRABCDE operon, which encodes the E.coli common pilus (ECP). ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition. Tip pilus adhesin, which is required for assembly of EcpA into fibers (By similarity)" GR_6 K10K4_RS09515 YES WP_086046865.1 invasin GR_6 K10K4_RS09520 YES WP_086046866.1 hypothetical protein COG5492 N Bacterial Ig-like domain 2 GR_6 K10K4_RS09525 YES WP_086046867.1 hypothetical protein "COG2885,COG3637" M Belongs to the ompA family GR_6 K10K4_RS09530 YES WP_086046868.1 hypothetical protein GR_6 K10K4_RS09535 YES WP_086046869.1 hypothetical protein COG3121 NU Chaperone GR_6 K10K4_RS09540 YES WP_086046870.1 hypothetical protein COG3188 NU E-set like domain GR_6 K10K4_RS09545 YES WP_086046871.1 hypothetical protein COG3188 NU E-set like domain GR_6 K10K4_RS09550 YES WP_086046872.1 hypothetical protein COG3188 NU E-set like domain GR_6 K10K4_RS09555 YES WP_086046873.1 hypothetical protein COG3188 NU E-set like domain GR_6 K10K4_RS09560 NO None hypothetical protein GR_6 K10K4_RS09565 YES WP_086046874.1 hypothetical protein GR_6 K10K4_RS09570 YES WP_086046875.1 "1,4-beta-D-glucan glucohydrolase" COG1472 G Belongs to the glycosyl hydrolase 3 family GR_6 K10K4_RS09575 YES None IS5/IS1182 family transposase COG3039 L User locus_tag GR_6 K10K4_RS09580 YES WP_086046876.1 hypothetical protein "COG0642,COG2205" T PhoQ Sensor GR_6 K10K4_RS09585 YES WP_086046877.1 DNA-binding response regulator COG2197 K "helix_turn_helix, Lux Regulon" GR_6 K10K4_RS09590 YES WP_086046878.1 hypothetical protein COG2197 K "helix_turn_helix, Lux Regulon" GR_6 K10K4_RS09595 NO None IS5/IS1182 family transposase GR_6 K10K4_RS09600 YES WP_086047147.1 transcriptional regulator COG2916 K Domain in histone-like proteins of HNS family GR_6 K10K4_RS09605 YES WP_086046879.1 AsnC family transcriptional regulator COG1522 K helix_turn_helix ASNC type GR_6 K10K4_RS09610 NO None IS5/IS1182 family transposase GR_6 K10K4_RS09615 YES WP_017635408.1 hypothetical protein GR_6 K10K4_RS09620 YES None hypothetical protein GR_6 K10K4_RS09625 NO WP_080996130.1 hypothetical protein GR_6 K10K4_RS09630 YES WP_054577321.1 hypothetical protein GR_6 K10K4_RS09635 NO WP_086047148.1 DUF3265 domain-containing protein GR_6 K10K4_RS09640 YES WP_050550131.1 IS30 family transposase COG2826 L "other refs with uncharged polar side chains (S Ser or T Thr), and there are a few more such examples along the aa-chain (ex R Arg changed with H His)" GR_6 K10K4_RS09645 YES WP_086046880.1 hypothetical protein "1N7TK@1224,1ST02@1236,1XZVB@135623,2B79J@1,320CA@2" S Protein of unknown function (DUF1643) GR_6 K10K4_RS09650 YES None "fructose 1,6-bisphosphatase" GR_6 K10K4_RS09655 NO WP_081008312.1 DUF3265 domain-containing protein GR_6 K10K4_RS09660 NO WP_005535745.1 cysteine hydrolase COG1335 Q COG1335 Amidases related to nicotinamidase GR_6 K10K4_RS09665 YES WP_017633499.1 hypothetical protein COG1335 Q COG1335 Amidases related to nicotinamidase GR_6 K10K4_RS09670 NO WP_080573844.1 hypothetical protein GR_6 K10K4_RS09675 YES WP_086046881.1 energy transducer TonB "COG0810,COG4219" U "Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins" GR_6 K10K4_RS09680 NO WP_086046882.1 DUF3265 domain-containing protein GR_6 K10K4_RS09685 YES WP_086046883.1 hypothetical protein GR_6 K10K4_RS09690 YES WP_054730956.1 hypothetical protein GR_6 K10K4_RS09695 YES WP_086046884.1 hypothetical protein GR_6 K10K4_RS09700 NO WP_081334108.1 hypothetical protein GR_6 K10K4_RS09705 NO WP_086046885.1 N-acetyltransferase "COG0454,COG0456" K Acetyltransferase (GNAT) domain GR_6 K10K4_RS09710 NO WP_080300716.1 hypothetical protein GR_6 K10K4_RS09715 YES WP_086046886.1 hypothetical protein GR_6 K10K4_RS09720 NO WP_086046887.1 DUF3265 domain-containing protein GR_6 K10K4_RS09725 NO WP_045616264.1 hypothetical protein GR_6 K10K4_RS09730 NO WP_080765045.1 hypothetical protein GR_6 K10K4_RS09735 NO WP_086046888.1 DUF3265 domain-containing protein GR_6 K10K4_RS09740 YES WP_086046889.1 hypothetical protein GR_6 K10K4_RS09745 NO WP_086028248.1 DUF3265 domain-containing protein GR_6 K10K4_RS09750 NO WP_017188030.1 hypothetical protein GR_6 K10K4_RS09755 NO WP_005377029.1 hypothetical protein GR_6 K10K4_RS09760 NO WP_086046890.1 DUF3265 domain-containing protein GR_6 K10K4_RS09765 YES WP_086046891.1 hypothetical protein GR_6 K10K4_RS09770 YES WP_025625190.1 DUF2132 domain-containing protein COG4628 S DNA-binding protein VF530 GR_6 K10K4_RS09775 NO WP_086046892.1 hypothetical protein COG3575 S Nucleotidyltransferase GR_6 K10K4_RS09780 NO WP_086046893.1 DUF3265 domain-containing protein GR_6 K10K4_RS09785 YES WP_086046894.1 hypothetical protein COG2810 L Type I restriction enzyme R protein N terminus (HSDR_N) GR_6 K10K4_RS09790 NO WP_086046895.1 DUF3265 domain-containing protein GR_6 K10K4_RS09795 NO WP_086046896.1 hypothetical protein GR_6 K10K4_RS09800 NO WP_078535048.1 hypothetical protein GR_6 K10K4_RS09805 NO WP_086046897.1 integrase COG0582 L Belongs to the 'phage' integrase family GR_6 K10K4_RS09810 NO WP_054574728.1 hypothetical protein "1R8TD@1224,1S0VX@1236,1XWZE@135623,2AQ2U@1,31F7Z@2" S Protein of unknown function (DUF2947) GR_6 K10K4_RS09815 NO WP_005376917.1 phosphohydrolase COG1896 S hydrolases of HD superfamily GR_7 K10K4_RS11740 NO WP_086046959.1 thioredoxin-dependent thiol peroxidase COG1225 O COG1225 Peroxiredoxin GR_7 K10K4_RS11745 YES WP_086046960.1 integrase COG4974 L Belongs to the 'phage' integrase family GR_7 K10K4_RS11750 YES WP_086046961.1 hypothetical protein GR_7 K10K4_RS11755 YES WP_086046962.1 integrase COG0582 L viral genome integration into host DNA GR_7 K10K4_RS11760 YES WP_086046963.1 bacterioferritin comigratory protein GR_7 K10K4_RS11765 YES WP_086046964.1 thioredoxin-dependent thiol peroxidase COG1225 O COG1225 Peroxiredoxin GR_7 K10K4_RS11770 YES WP_086046965.1 resolvase COG1961 L "Resolvase, N terminal domain" GR_7 K10K4_RS11775 NO None transcriptional regulator GR_7 K10K4_RS11780 NO None fumarate reductase (quinol) flavoprotein subunit GR_7 K10K4_RS11785 YES WP_086046966.1 peptidase C39 COG2274 V abc transporter GR_7 K10K4_RS11790 YES WP_069546416.1 hypothetical protein COG0845 M HlyD family secretion protein GR_7 K10K4_RS11795 YES WP_086047154.1 radical SAM protein COG0535 S Radical SAM superfamily GR_7 K10K4_RS11800 YES WP_069546414.1 hypothetical protein COG0535 S Radical SAM superfamily GR_7 K10K4_RS11805 YES WP_069546413.1 hypothetical protein COG0535 S Radical SAM superfamily GR_7 K10K4_RS11810 YES WP_069546412.1 chitin synthase COG1215 M Glycosyl transferase family group 2 GR_7 K10K4_RS11815 YES WP_086046967.1 MchC protein COG0397 S "Uncharacterized ACR, YdiU/UPF0061 family" GR_7 K10K4_RS11820 YES WP_069546446.1 toxin-activating lysine-acyltransferase GR_7 K10K4_RS11825 NO None hypothetical protein GR_7 K10K4_RS11830 YES WP_086046968.1 hypothetical protein GR_7 K10K4_RS11835 YES WP_086046969.1 hypothetical protein "1QKJU@1224,1TIQ2@1236,1XZFW@135623,2AWYH@1,31NW8@2" L "Bacterial regulatory protein, Fis family" GR_7 K10K4_RS11840 YES WP_086046970.1 hypothetical protein COG3950 S AAA ATPase domain GR_7 K10K4_RS11845 YES WP_069522896.1 hypothetical protein COG0210 L DNA helicase GR_7 K10K4_RS11850 YES WP_029844913.1 ATP-binding protein COG3950 S AAA ATPase domain GR_7 K10K4_RS11855 YES WP_086046971.1 hypothetical protein COG1403 V HNH endonuclease GR_7 K10K4_RS11860 YES WP_086046972.1 hybrid sensor histidine kinase/response regulator COG0642 T His Kinase A (phospho-acceptor) domain GR_7 K10K4_RS11865 NO None IS3 family transposase GR_7 K10K4_RS11870 NO WP_005379019.1 cold-shock protein COG1278 K COG1278 Cold shock proteins GR_7 K10K4_RS11875 NO WP_005379017.1 hypothetical protein GR_7 K10K4_RS11880 NO WP_078580915.1 hypothetical protein GR_7 K10K4_RS11885 YES WP_086013888.1 hypothetical protein GR_7 K10K4_RS11890 NO WP_005379008.1 cold-shock protein COG1278 K Cold shock protein domain GR_7 K10K4_RS11895 YES WP_086046973.1 integrase COG0582 L Integrase GR_7 K10K4_RS11900 YES WP_086046974.1 HflK protein COG0330 O HflC and HflK could encode or regulate a protease GR_7 K10K4_RS11905 YES WP_024703481.1 protease modulator HflC COG0330 O HflC and HflK could regulate a protease GR_7 K10K4_RS11910 YES WP_086046975.1 Na+/H+ antiporter NhaA COG3004 P ) H( ) antiporter that extrudes sodium in exchange for external protons GR_7 K10K4_RS11915 YES WP_086046976.1 aconitate hydratase 1 COG1048 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate GR_7 K10K4_RS11920 YES WP_005378997.1 cold-shock protein COG1278 K Cold shock GR_7 K10K4_RS11925 YES WP_005378993.1 hypothetical protein GR_8 K10K4_RS12325 YES WP_086046982.1 hypothetical protein GR_8 K10K4_RS12330 YES WP_086046983.1 hypothetical protein COG0582 L viral genome integration into host DNA GR_8 K10K4_RS12335 YES WP_085344067.1 hypothetical protein GR_8 K10K4_RS12340 YES WP_086046984.1 integrase COG4974 L Phage Integrase Family GR_8 K10K4_RS12345 YES WP_086046985.1 DNA polymerase IV COG0389 L "Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII" GR_8 K10K4_RS12350 NO None transcriptional regulator GR_8 K10K4_RS12355 YES WP_086046986.1 hypothetical protein GR_8 K10K4_RS12360 YES WP_086046987.1 hypothetical protein GR_8 K10K4_RS12365 YES WP_086046988.1 hypothetical protein COG4104 S PAAR repeat-containing protein GR_8 K10K4_RS12370 YES WP_078558836.1 hypothetical protein COG1479 S Protein of unknown function DUF262 GR_8 K10K4_RS12375 NO None hypothetical protein GR_8 K10K4_RS12380 YES WP_078558838.1 hypothetical protein GR_8 K10K4_RS12385 YES WP_086046989.1 hypothetical protein GR_8 K10K4_RS12390 YES WP_017821094.1 hypothetical protein GR_8 K10K4_RS12395 YES WP_086046990.1 hypothetical protein COG4104 S PAAR repeat-containing protein GR_8 K10K4_RS12400 YES WP_086046991.1 patatin COG3621 S PFAM Patatin-like phospholipase GR_8 K10K4_RS12405 YES WP_023624321.1 hypothetical protein GR_8 K10K4_RS12410 YES WP_086046992.1 hypothetical protein COG0476 H ThiF family GR_8 K10K4_RS12415 YES WP_023624319.1 peptidase COG1310 S Prokaryotic homologs of the JAB domain GR_8 K10K4_RS12420 YES WP_086046993.1 diguanylate cyclase COG1061 L "Type III restriction enzyme, res subunit" GR_8 K10K4_RS12425 YES WP_023624318.1 hypothetical protein GR_8 K10K4_RS12430 YES WP_078558833.1 transcriptional regulator COG1396 K Helix-turn-helix GR_8 K10K4_RS12435 YES WP_054579191.1 sodium-independent anion transporter COG0659 P COG0659 Sulfate permease and related transporters (MFS superfamily) GR_8 K10K4_RS12440 YES WP_086046994.1 universal stress protein UspA COG0589 T Universal stress protein family GR_8 K10K4_RS12445 YES WP_085344734.1 GNAT family N-acetyltransferase "COG0454,COG0456" K Acetyltransferase (GNAT) domain GR_8 K10K4_RS12450 YES WP_054390489.1 hypothetical protein GR_8 K10K4_RS12455 YES WP_086046995.1 hypothetical protein "1P7PU@1224,1SUQ9@1236,1XU6E@135623,2B0RV@1,2ZXQR@2" S Protein of unknown function (DUF2913) GR_8 K10K4_RS12460 YES WP_086046996.1 hypothetical protein "2EFSM@1,339IM@2" S Protein of unknown function (DUF4238) GR_8 K10K4_RS12465 NO WP_086046997.1 DUF3265 domain-containing protein GR_8 K10K4_RS12470 NO WP_086046998.1 hypothetical protein GR_8 K10K4_RS12475 YES WP_086047156.1 hypothetical protein GR_9 K10K4_RS12710 NO None IS3 family transposase GR_9 K10K4_RS12715 YES WP_054728388.1 HNH endonuclease COG3440 V regulation of methylation-dependent chromatin silencing GR_9 K10K4_RS12720 YES WP_054728385.1 DNA (cytosine-5-)-methyltransferase COG0270 L C-5 cytosine-specific DNA methylase GR_9 K10K4_RS12725 YES WP_054728382.1 DNA (cytosine-5-)-methyltransferase COG0270 L cytosine-specific methyltransferase